Galectin-8 Recombinant Protein | LGALS8 recombinant protein

Recombinant Human Galectin-8 protein, N-His Tag and C-DYKDDDDK Tag

Cat. Num. AAA157981

• Gene Names: LGALS8; Gal-8; PCTA1; PCTA-1; Po66-CBP
• Purity: >90% as determined by SDS-PAGE
• Synonyms: Galectin-8; Recombinant Human Galectin-8 protein; N-His Tag and C-DYKDDDDK Tag; LGALS8 recombinant protein

• Host: Mammalian cells
• Purity/Purification: >90% as determined by SDS-PAGE
• Form/Format: Lyophilized. Lyophilized from 20mM HEPES, 10mM Tris-HCl, 50mM NaCl, pH 7.5, 5% Trehalose, 5% Mannose, 1mM EDTA.

• Species: Human
• Endotoxin level: <1.0EU per ug of the protein as determined by the LAL method
• Reconstitution: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details
• Construction: A DNA sequence encoding the human LGALS8 (Met1~Trp317) was fused with the N-terminal His Tag and C- terminal DYKDDDDK Tag
• Preparation and Storage: Store at 2 to 8 degree C for one week. Store at -20 to -80 degree C for twelve months from the date of receipt. Use a manual defrost freezer and avoid repeated freeze thaw cycles.; Shipping: In general, proteins are provided as lyophilized powder/frozen liquid.

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NCBI and Uniprot Product Information

• NCBI GI #: 42544185
• NCBI GeneID: 3964
• NCBI Accession #: NP_006490.3
• NCBI GenBank Nucleotide #: NM_006499.4
• UniProt Accession #: O00214; O15215; Q5T3P5; Q5T3Q4; Q8TEV1; Q96B92; Q9BXC8; Q9H584; Q9H585; Q9UEZ6; Q9UP32; Q9UP33
• Molecular Weight: 35,808 Da
• NCBI Official Full Name: galectin-8 isoform a
• NCBI Official Synonym Full Names: lectin, galactoside-binding, soluble, 8
• NCBI Official Symbol: LGALS8
• NCBI Official Synonym Symbols: Gal-8; PCTA1; PCTA-1; Po66-CBP
• NCBI Protein Information: galectin-8; galectin 8; galectin-8g; Po66 carbohydrate binding protein; po66 carbohydrate-binding protein; prostate carcinoma tumor antigen 1
• UniProt Protein Name: Galectin-8
• Protein Family: Galectin
• UniProt Gene Name: LGALS8
• UniProt Synonym Gene Names: Gal-8; Po66-CBP; PCTA-1
• UniProt Entry Name: LEG8_HUMAN

NCBI Description

This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

LGALS8: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion

Chromosomal Location of Human Ortholog: 1q43

Cellular Component: extracellular space; membrane; cytoplasm

Molecular Function: protein binding; carbohydrate binding

Biological Process: plasma cell differentiation; T cell costimulation