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SDS-Page

LGALS1 recombinant protein

LGALS1, 1-135aa, mouse, His tag, E Coli

Gene Names
Lgals1; L14; Gal-1; Galbp; L-14.5; Lect14; AA410090; galectin-1
Applications
SDS-Page
Purity
> 95% by SDS-PAGE
Synonyms
LGALS1; 1-135aa; mouse; His tag; E Coli; Galectin-1; AA410090; Gal-1; Galbp; galectin-1; L-14.5; L14; Lect14; LGALS1 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol
Concentration
1 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMACGLV ASNLNLKPGE CLKVRGEVAS DAKSFVLNLG KDSNNLCLHF NPRFNAHGDA NTIVCNTKED GTWGTEHREP AFPFQPGSIT EVCITFDQAD LTIKLPDGHE FKFPNRLNME AINYMAADGD FKIKCVAFE
Sequence Length
135
Applicable Applications for LGALS1 recombinant protein
SDS-PAGE
Antigen Species
Mouse
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

SDS-Page

SDS-Page
Related Product Information for LGALS1 recombinant protein
LGALS1 is a member of the beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This protein is an autocrine negative growth factor that regulates cell proliferation. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes, thus LGALS1 has immunosuppressive and anti-inflammatory properties. LGALS1 also regulates tumor angiogenesis and is a target for angiostatic cancer therapy. Recombinant mouse LGALS1 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques
Product Categories/Family for LGALS1 recombinant protein
References
Ilarregui JM., et al. (2009). Nat Immunol. 10 (9):981-91.; Gauthier L., Proc Natl Acad Sci u S A. 2002 Oct 1;99 (20):13014-9.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
17 kDa (159aa), confirmed by MALDI-TOF
NCBI Official Full Name
galectin-1
NCBI Official Synonym Full Names
lectin, galactose binding, soluble 1
NCBI Official Symbol
Lgals1
NCBI Official Synonym Symbols
L14; Gal-1; Galbp; L-14.5; Lect14; AA410090; galectin-1
NCBI Protein Information
galectin-1
UniProt Protein Name
Galectin-1
UniProt Gene Name
Lgals1
UniProt Synonym Gene Names
Gbp; Gal-1

Uniprot Description

Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.

Research Articles on LGALS1

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Product Notes

The LGALS1 lgals1 (Catalog #AAA204559) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's LGALS1 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the LGALS1 lgals1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MGSHMACGLV ASNLNLKPGE CLKVRGEVAS DAKSFVLNLG KDSNNLCLHF NPRFNAHGDA NTIVCNTKED GTWGTEHREP AFPFQPGSIT EVCITFDQAD LTIKLPDGHE FKFPNRLNME AINYMAADGD FKIKCVAFE. It is sometimes possible for the material contained within the vial of "LGALS1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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