SC65 Blocking Peptide | LEPREL4 blocking peptide

SC65 Antibody (C-term) Blocking peptide

• Gene Names: P3H4; NO55; SC65; NOL55; LEPREL4
• Synonyms: SC65; SC65 Antibody (C-term) Blocking peptide; Synaptonemal complex protein SC65; Leprecan-like protein 4; Nucleolar autoantigen No55; LEPREL4; NOL55; LEPREL4 blocking peptide

• Specificity: The synthetic peptide sequence used to generate the antibody was selected from the C-term region of SC65. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 437

• Cellular Location: Nucleus, nucleolus. Chromosome. Note: Localized uniformly throughout the granular component of the nucleolus and on the surface of chromosomes during mitosis
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 3183090
• NCBI GeneID: 10609
• UniProt Accession #: Q92791; Q53GI6; Q9H4F6
• Molecular Weight: 50,381 Da
• NCBI Official Full Name: Synaptonemal complex protein SC65
• NCBI Official Synonym Full Names: prolyl 3-hydroxylase family member 4 (non-enzymatic)
• NCBI Official Symbol: P3H4
• NCBI Official Synonym Symbols: NO55; SC65; NOL55; LEPREL4
• NCBI Protein Information: synaptonemal complex protein SC65
• UniProt Protein Name: Synaptonemal complex protein SC65
• UniProt Gene Name: P3H4
• UniProt Entry Name: SC65_HUMAN

NCBI Description

This nucleolar protein was first characterized because it was an autoantigen in cases on interstitial cystitis. The protein, with a predicted molecular weight of 50 kDa, appears to be localized in the particulate compartment of the interphase nucleolus, with a distribution distinct from that of nucleolar protein B23. During mitosis it is associated with chromosomes. [provided by RefSeq, Jul 2008]

Uniprot Description

SC65: This nucleolar protein was first characterized because it was an autoantigen in cases on interstitial cystitis. The protein, with a predicted molecular weight of 50 kDa, appears to be localized in the particulate compartment of the interphase nucleolus, with a distribution distinct from that of nucleolar protein B23. During mitosis it is associated with chromosomes. [provided by RefSeq, Jul 2008]

Protein type: Unknown function; Nucleolus

Chromosomal Location of Human Ortholog: 17q21.2

Cellular Component: condensed nuclear chromosome

Biological Process: synaptonemal complex assembly