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Left/Right Determination Factor 2 Recombinant Protein | LEFTY2 recombinant protein

Recombinant Left/Right Determination Factor 2 (LEFTY2)

Gene Names
Lefty2; Ebaf; Lefta; Leftb; lefty-2; lefty-B; 6030463A22Rik
Applications
SDS-Page, Western Blot
Purity
>97%
Synonyms
Left/Right Determination Factor 2; Recombinant Left/Right Determination Factor 2 (LEFTY2); TGFB4; EBAF; LEFTA; LEFTYA; Endometrial Bleeding Associated Factor; Left-right determination factor A; Transforming growth factor beta-4; LEFTY2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
>97%
Form/Format
Freeze-dried powder
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Sequence Length
368
Applicable Applications for LEFTY2 recombinant protein
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
Source
Prokaryotic expression
Species
Mouse
Tag
N-terminal His Tag
Reconstitution
Reconstitute in PBS or others.
Preparation and Storage
Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Avoid repeated freeze/thaw cycles.
Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Product Categories/Family for LEFTY2 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
left-right determination factor 2 preproprotein
NCBI Official Synonym Full Names
left-right determination factor 2
NCBI Official Symbol
Lefty2
NCBI Official Synonym Symbols
Ebaf; Lefta; Leftb; lefty-2; lefty-B; 6030463A22Rik
NCBI Protein Information
left-right determination factor 2
UniProt Protein Name
Left-right determination factor 2
UniProt Gene Name
Lefty2
UniProt Synonym Gene Names
Leftb

NCBI Description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. This protein is also important in self-renewal and differentiation of mouse embryonic stem cells. Mice lacking a functional copy of this gene exhibit defects in axial and left-right patterning. [provided by RefSeq, Aug 2016]

Uniprot Description

Required for left-right asymmetry determination of organ systems in mammals.

Research Articles on LEFTY2

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Product Notes

The LEFTY2 lefty2 (Catalog #AAA2123077) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Left/Right Determination Factor 2 can be used in a range of immunoassay formats including, but not limited to, Positive Control, Immunogen, SDS-PAGE, Western Blot (WB). Researchers should empirically determine the suitability of the LEFTY2 lefty2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Left/Right Determination Factor 2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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