NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of family 1 glycosidases. Glycosidases are enzymes that hydrolyze glycosidic bonds and are classified into families based on primary amino acid sequence. Most members of family 1 have two conserved glutamic acid residues, which are required for enzymatic activity. The mouse ortholog of this protein has been characterized and has a domain structure of an N-terminal signal peptide, glycosidase domain, transmembrane domain, and a short cytoplasmic tail. It lacks one of the conserved glutamic acid residues important for catalysis, and its function remains to be determined (PMID: 12084582). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Uniprot Description
Klotho gamma: Belongs to the glycosyl hydrolase 1 family. Klotho subfamily.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 15q22.31
Cellular Component: brush border; endoplasmic reticulum; endoplasmic reticulum membrane; integral component of membrane
Molecular Function: beta-glucosidase activity
Biological Process: carbohydrate metabolic process
Research Articles on Lctl
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Product Notes
The Mouse Lctl lctl (Catalog #AAA2888282) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2888282 ELISA Kit recognizes Mouse Lctl. It is sometimes possible for the material contained within the vial of "Lactase-like protein, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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