Serine palmitoyltransferase 1 (lcb1) Recombinant Protein | SPBC18E5.02c recombinant protein
Recombinant Schizosaccharomyces pombe Serine palmitoyltransferase 1 (lcb1)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Serine palmitoyltransferase 1 (lcb1); Recombinant Schizosaccharomyces pombe Serine palmitoyltransferase 1 (lcb1); Recombinant Serine palmitoyltransferase 1 (lcb1); Serine palmitoyltransferase 1; SPT 1; SPT1 EC= 2.3.1.50; Long chain base biosynthesis protein 1; SPBC18E5.02c recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-509
Sequence
MSYSYPFFDDVYAYYNQTVTFFGKALDVLPGSPIVKRYIKSSYQNDPLRTFIEFLLLVFAAYYVLRKPRTSPDNNYVEFTEKEINELVDDWKPEPLVAELTDVEKLELKSIPVLESVHLHTKLIDGRPITNFASFNFLDLAENKHITECAVATLRECGLGACGPPGFYGTQDKHLRLEKDIASFIGVERAIVYAQSFQTISSVIPAFSKRGDILVVDEACNFAIQKGIQISRTTIRYFKHNNMKDLERILQELEDDFVKHNRPLTRRFIITEGISENYGDMVDLTKIVALKKKYKYRLILDETWSFGTCGRTGKGLTEHFGVPPTDVEIIIGSLTTSLAGGGGFCAGSELMVEHQRLSGMAYIYSAALPASLAVAAYEAISILSRDGGSMLNDLRSKSALFHAKLSRNKFFETSSDIESPIIHLRFKDKDISHDKQVFLLEEIVELCIAEGFLIARAKRVESLERVKVQPSLRICISTGHSAEEIEKLALLIKEKTEIVFDKHKVINQV
Sequence Length
509
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
57,469 Da
NCBI Official Full Name
serine palmitoyltransferase complex subunit (predicted)
NCBI Official Symbol
SPBC18E5.02c
NCBI Protein Information
serine palmitoyltransferase complex subunit (predicted)
UniProt Protein Name
Serine palmitoyltransferase 1
UniProt Gene Name
lcb1
UniProt Synonym Gene Names
SPT 1; SPT1
UniProt Entry Name
LCB1_SCHPO
Uniprot Description
Function: Component of serine palmitoyltransferase (SPT), which catalyzes the committed step in the synthesis of sphingolipids, the condensation of serine with palmitoyl CoA to form the long chain base 3-ketosphinganine
By similarity. UniProtKB P25045
Catalytic activity: Palmitoyl-CoA + L-serine = CoA + 3-dehydro-D-sphinganine + CO2. UniProtKB P25045
Cofactor: Pyridoxal phosphate
By similarity. UniProtKB P25045
Pathway: Lipid metabolism; sphingolipid metabolism. UniProtKB P25045
Subunit structure: Lcb1 and lcb2 encode essential subunits of the enzyme and form a heterodimer
By similarity. UniProtKB P25045
Subcellular location: Cytoplasm
By similarity. Endoplasmic reticulum. Membrane; Multi-pass membrane protein
Potential Ref.2 UniProtKB P25045.
Sequence similarities: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
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Product Notes
The SPBC18E5.02c lcb1 (Catalog #AAA1092504) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-509. The amino acid sequence is listed below: MSYSYPFFDD VYAYYNQTVT FFGKALDVLP GSPIVKRYIK SSYQNDPLRT FIEFLLLVFA AYYVLRKPRT SPDNNYVEFT EKEINELVDD WKPEPLVAEL TDVEKLELKS IPVLESVHLH TKLIDGRPIT NFASFNFLDL AENKHITECA VATLRECGLG ACGPPGFYGT QDKHLRLEKD IASFIGVERA IVYAQSFQTI SSVIPAFSKR GDILVVDEAC NFAIQKGIQI SRTTIRYFKH NNMKDLERIL QELEDDFVKH NRPLTRRFII TEGISENYGD MVDLTKIVAL KKKYKYRLIL DETWSFGTCG RTGKGLTEHF GVPPTDVEII IGSLTTSLAG GGGFCAGSEL MVEHQRLSGM AYIYSAALPA SLAVAAYEAI SILSRDGGSM LNDLRSKSAL FHAKLSRNKF FETSSDIESP IIHLRFKDKD ISHDKQVFLL EEIVELCIAE GFLIARAKRV ESLERVKVQP SLRICISTGH SAEEIEKLAL LIKEKTEIVF DKHKVINQV. It is sometimes possible for the material contained within the vial of "Serine palmitoyltransferase 1 (lcb1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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