L-amino-acid oxidase Recombinant Protein | LAAO recombinant protein
Recombinant Aplysia dactylomela L-amino-acid oxidase
NCBI and Uniprot Product Information
Uniprot Description
Function: Catalyzes the oxidative deamination of positively charged L-amino acids L-Lys and L-Arg but not of amino acids L-His, L-Asp or L-Glu. Has antibacterial activity against the Gram-positive bacterium S.aureus (MIC=15 µg/ml). This antibacterial activity is bacteriostatic in the absence of amino acids L-Lys or L-Arg but bactericidal in their presence. The antibacterial effect is largely dependent on H2O2 produced in the oxidative deamination of substrates. Has hemagglutinating activity towards rabbit erythrocytes. Hemagglutinating activity is inhibited by the glycoprotein fetuin, but not by glucose, mannose, galactose, N-acetylglucosamine, N-acetylgalactosamine or sialic acid. Ref.1 Ref.2
Catalytic activity: An L-amino acid + H2O + O2 = a 2-oxo acid + NH3 + H2O2. Ref.1
Cofactor: FAD. Ref.1
Subunit structure: Monomer. Ref.2
Subcellular location: Secreted Ref.1 Ref.2 Ref.4.
Tissue specificity: Expressed by the ink gland. Ref.4
Post-translational modification: Not glycosylated. Ref.2 Ref.3
Sequence similarities: Belongs to the flavin monoamine oxidase family.
Biophysicochemical propertiesKinetic parameters:KM=0.22 mM for L-Lys Ref.1KM=0.015 mM for L-Arg Ref.1pH dependence:Optimum pH is 8. More than 50% activity is retained between pH 3 and 12. Inactive at pH 2. Ref.1Temperature dependence:Activity remains stable after 30 min at 55 degrees Celsius. Ref.1
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Product Notes
The L-amino-acid oxidase laao (Catalog #AAA1112015) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-26aa; full length protein. The amino acid sequence is listed below: DGVCSNRRQC NKEVCGSSYD VAIVGA. It is sometimes possible for the material contained within the vial of "L-amino-acid oxidase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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