Peripentonal hexon-associated protein (PIIIA) Recombinant Protein | PIIIA recombinant protein

Recombinant Human adenovirus C serotype 2 Peripentonal hexon-associated protein (PIIIA), partial

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Peripentonal hexon-associated protein (PIIIA); Recombinant Human adenovirus C serotype 2 Peripentonal hexon-associated protein (PIIIA); partial; PIIIA recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 585

• Species: Human adenovirus C serotype 2 (HAdV-2) (Human adenovirus 2)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 56160494
• NCBI Accession #: AP_000169.1
• NCBI GenBank Nucleotide #: AC_000007.1
• UniProt Accession #: P03279
• Molecular Weight: 65,287 Da
• NCBI Official Full Name: pIIIa
• UniProt Protein Name: Pre-hexon-linking protein IIIa
• UniProt Gene Name: L1
• UniProt Synonym Gene Names: CVSC

Uniprot Description

Structural component of the virion that acts as a cement protein on the capsid exterior which mediates the interactions between the hexons, including the peripentonal hexons, and reaches all the way to the penton vertices. Two hexon linking proteins IIIa, one from each facet, stabilize the unique edge interface between a pair of facets. As the virus enters the host cell, hexon linking proteins IIIa are shed concomitant with virion acidification in the endosome. During virus assembly, seems to play a role in the serotype specificity of the packaging of viral DNA via its interaction with packaging protein 3.