Keratin, type I cytoskeletal 13 (KRT13) Recombinant Protein | KRT13 recombinant protein

Recombinant Human Keratin, type I cytoskeletal 13 (KRT13)

Cat. Num. AAA948396

• Gene Names: KRT13; K13; CK13; WSN2
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Keratin; type I cytoskeletal 13 (KRT13); Recombinant Human Keratin; KRT13 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-458aa; Full Length
• Sequence: MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHTKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTSSASVTTTSNASGRRTSDVRRP

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for KRT13 recombinant protein

This protein is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described.

NCBI and Uniprot Product Information

• NCBI GI #: 131412228
• NCBI GeneID: 3860
• NCBI Accession #: NP_002265.2
• NCBI GenBank Nucleotide #: NM_002274.3
• UniProt Accession #: P13646; Q53G54; Q6AZK5; Q8N240
• Molecular Weight: 45,867 Da
• NCBI Official Full Name: keratin, type I cytoskeletal 13 isoform b
• NCBI Official Synonym Full Names: keratin 13
• NCBI Official Symbol: KRT13
• NCBI Official Synonym Symbols: K13; CK13; WSN2
• NCBI Protein Information: keratin, type I cytoskeletal 13
• UniProt Protein Name: Keratin, type I cytoskeletal 13
• Protein Family: Keratin
• UniProt Gene Name: KRT13
• UniProt Synonym Gene Names: CK-13; K13

NCBI Description

The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

MiscellaneousThere are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).