Typical Testing Data/Standard Curve (for reference only)
Mouse KREMEN ELISA Kit | KREMEN1 elisa kit
Mouse KREMEN ELISA Kit
Gene Names
Kremen1; Krm1; Kremen; AV002070
Reactivity
Mouse
Synonyms
KREMEN; Mouse KREMEN ELISA Kit; KRM1; Kremen protein 1; Dickkopf receptor; Kringle domain-containing transmembrane protein 1; Kringle-containing protein marking the eye and the nose; KREMEN1 elisa kit
Reactivity
Mouse
Specificity
The Mouse KREMEN ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Mouse KREMEN proteins within the range of 125 pg/ml - 8000 pg/ml.
Sequence Length
473
Samples
Cell Culture Supernates, Serum, Plasma
Sensitivity
<10 pg/ml
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for KREMEN1 elisa kit
Principle of the Assay: The Mouse KREMEN ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Mouse KREMEN in Cell Culture Supernates, Serum, Plasma. This assay employs an antibody specific for Mouse KREMEN coated on a 96-well plate. Standards and samples are pipetted into the wells and KREMEN present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Mouse KREMEN antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of KREMEN bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.
Background: Kremen protein 1 is a protein that in humans is encoded by the KREMEN1 gene. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
Background: Kremen protein 1 is a protein that in humans is encoded by the KREMEN1 gene. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
51,673 Da
NCBI Official Full Name
kremen protein 1
NCBI Official Synonym Full Names
kringle containing transmembrane protein 1
NCBI Official Symbol
Kremen1
NCBI Official Synonym Symbols
Krm1; Kremen; AV002070
NCBI Protein Information
kremen protein 1
UniProt Protein Name
Kremen protein 1
Protein Family
UniProt Gene Name
Kremen1
UniProt Synonym Gene Names
Kremen
UniProt Entry Name
KREM1_MOUSE
Uniprot Description
KREMEN1: Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, misc.
Cellular Component: membrane
Biological Process: cell communication
Research Articles on KREMEN1
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Product Notes
The Mouse KREMEN1 kremen1 (Catalog #AAA8248444) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA8248444 ELISA Kit recognizes Mouse KREMEN1. It is sometimes possible for the material contained within the vial of "KREMEN, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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