Histone-lysine N-methyltransferase SUV420H1 (Suv420h1) Recombinant Protein | Suv420h1 recombinant protein

Recombinant Rat Histone-lysine N-methyltransferase SUV420H1 (Suv420h1) , partial

• Gene Names: Kmt5b; Suv420h1
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Histone-lysine N-methyltransferase SUV420H1 (Suv420h1); Recombinant Rat Histone-lysine N-methyltransferase SUV420H1 (Suv420h1); partial; Suv420h1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 883

• Species: Rat
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for Suv420h1 recombinant protein

This gene encodes a protein that contains a SET domain. SET domains appear to be protein-protein interaction domains that mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases (dsPTPases). The function of this gene has not been determined. Two alternatively spliced transcript variants have been found for this gene.

NCBI and Uniprot Product Information

• NCBI GI #: 157817845
• NCBI GeneID: 361688
• NCBI Accession #: NP_001101982.1
• NCBI GenBank Nucleotide #: NM_001108512.1
• UniProt Accession #: P0C2N5
• Molecular Weight: 98,668 Da
• NCBI Official Full Name: histone-lysine N-methyltransferase KMT5B
• NCBI Official Synonym Full Names: lysine methyltransferase 5B
• NCBI Official Symbol: Kmt5b
• NCBI Official Synonym Symbols: Suv420h1
• NCBI Protein Information: histone-lysine N-methyltransferase KMT5B
• UniProt Protein Name: Histone-lysine N-methyltransferase KMT5B
• UniProt Gene Name: Kmt5b
• UniProt Synonym Gene Names: Su(var)4-20 homolog 1; Suv4-20h1

Uniprot Description

Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2). Plays a role in myogenesis by regulating the expression of target genes, such as EID3 ().