SDS-Page
(Recombinant Human CD94/Natural Killer Cells Antigen CD94 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.)
CD94/Natural Killer Cells Antigen CD94 Recombinant Protein | CD94 recombinant protein
Recombinant Human CD94/Natural Killer Cells Antigen CD94 Protein
After reconstitution, the protein solution is stable at -20 degree C for 3 months, at 2-8 degree C for up to 1 week.
SDS-Page
(Recombinant Human CD94/Natural Killer Cells Antigen CD94 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.)
SDS-Page
(Recombinant Human CD94/Natural Killer Cells Antigen CD94 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.)
Background: CD94 (Cluster of Differentiation 94), also known as killer cell lectin-like receptor subfamily D member 1(KLRD1), is expressed on the surface of natural killer cells in the innate immune system. CD94 Plays a role as areceptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. CD94 Canform disulfide-bonded heterodimer with NKG2 family members. The CD94/NKG2 complex, on the surface ofnatural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells. Natural killer (NK) cells are adistinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immunestimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, areexpressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigenpreferentially expressed on NK cells and is classified as a type II membrane protein because it has an external Cterminus.
NCBI and Uniprot Product Information
NCBI Description
Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017]
Uniprot Description
KLRD1: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 12p13
Cellular Component: integral to membrane; plasma membrane; receptor complex; external side of plasma membrane
Molecular Function: protein binding; transmembrane receptor activity; carbohydrate binding
Biological Process: regulation of immune response; cell surface receptor linked signal transduction; natural killer cell mediated immunity; innate immune response
Research Articles on CD94
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Product Notes
The CD94 klrd1 (Catalog #AAA9139999) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: SFTKLSIEPA FTPGPNIELQ KDSDCCSCQE KWVGYRCNCY FISSEQKTWN ESRHLCASQK SSLLQLQNTD ELDFMSSSQQ FYWIGLSYSE EHTAWLWENG SALSQYLFPS FETFNTKNCI AYNPNGNALD ESCEDKNRYI CKQQLI. It is sometimes possible for the material contained within the vial of "CD94/Natural Killer Cells Antigen CD94, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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