Killer Cell Lectin-Like Receptor Subfamily C, Member 1 Recombinant Protein | KLRC1 recombinant protein

Recombinant Human Killer Cell Lectin-Like Receptor Subfamily C, Member 1

Cat. Num. AAA147229

• Gene Names: KLRC1; NKG2; NKG2A; CD159A
• Purity: Greater than 90.0% as determined by SDS-PAGE
• Synonyms: Killer Cell Lectin-Like Receptor Subfamily C; Member 1; Recombinant Human Killer Cell Lectin-Like Receptor Subfamily C; NKG2-A/NKG2-B type II integral membrane protein isoform NKG2-A; KLRC1; CD159A; NKG2; NKG2A; CD159 antigen-like family member A; NK cell receptor A; NKG2-A/B-activating NK receptor; KLRC1 Human; Member 1 Human Recombinant; KLRC1 recombinant protein

• Host: Sf9, Baculovirus cells
• Purity/Purification: Greater than 90.0% as determined by SDS-PAGE
• Form/Format: Sterile filtered colorless solution; Protein solution (0.25mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol
• Sequence: ADP PSTLIQR HNNSSLNTRT QKARHCGHCP EEWITYSNSC YYIGKERRTW EESLLACTSK NSSLLSIDNE EEMKFLSIIS PSSWIGVFRN SSHHPWVTMN GLAFKHEIKD SDNAELNCAV LQVNRLKSAQ CGSSIIYHCK HKLHHHHHH
• Sequence Length: 233

• Preparation and Storage: Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at-20 degree C for longer periods of time.; For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).; Avoid multiple freeze-thaw cycles

Related Product Information for KLRC1 recombinant protein

Description: KLRC1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 149 amino acids (94-233a.a.) and having a molecular mass of 17.1kDa (Molecular size on SDS-PAGE will appear at approximately 18-28kDa). KLRC1 is expressed with a 9 amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques.
Introduction: Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) is a part of the killer cell lectin-like receptor family. KLRC1 functions as a receptor for the detection of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRC1 is also connects with CD94 and is expressed on NK cells and some activated T cell.

Product Categories/Family for KLRC1 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Killer Cell Lectin-like Receptor; KLRC1 Human

NCBI and Uniprot Product Information

• NCBI GI #: 317373399
• NCBI GeneID: 3821
• UniProt Accession #: P26715
• Molecular Weight: 24,250 Da
• NCBI Official Full Name: NKG2-A/NKG2-B type II integral membrane protein
• NCBI Official Synonym Full Names: killer cell lectin like receptor C1
• NCBI Official Symbol: KLRC1
• NCBI Official Synonym Symbols: NKG2; NKG2A; CD159A
• NCBI Protein Information: NKG2-A/NKG2-B type II integral membrane protein
• UniProt Protein Name: NKG2-A/NKG2-B type II integral membrane protein
• UniProt Gene Name: KLRC1
• UniProt Synonym Gene Names: NKG2A

NCBI Description

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jan 2015]

Uniprot Description

Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.