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Kallikrein-8 (Klk8) Recombinant Protein | Klk8 recombinant protein
Recombinant Mouse Kallikrein-8 (Klk8)
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NCBI and Uniprot Product Information
Uniprot Description
KLK8: Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer- collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte proliferation. Plays a role in the secondary phase of pathogenesis following spinal cord injury. Belongs to the peptidase S1 family. Kallikrein subfamily. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Protease; EC 3.4.21.118; Secreted; Cell development/differentiation; Secreted, signal peptide
Cellular Component: extracellular space; cytoplasm; extracellular region
Molecular Function: peptidase activity; hydrolase activity; serine-type peptidase activity; serine-type endopeptidase activity; catalytic activity
Biological Process: cell death; negative regulation of myelination; negative regulation of axon regeneration; response to wounding; synapse organization and biogenesis; regulation of synapse organization and biogenesis; keratinocyte proliferation; proteolysis; neurite morphogenesis; memory
Research Articles on Klk8
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Product Notes
The Klk8 klk8 (Catalog #AAA1436257) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 33-260aa; Full Length of Mature Protein. The amino acid sequence is listed below: ILEGRECIPH SQPWQAALFQ GERLICGGVL VGDRWVLTAA HCKKQKYSVR LGDHSLQSRD QPEQEIQVAQ SIQHPCYNNS NPEDHSHDIM LIRLQNSANL GDKVKPVQLA NLCPKVGQKC IISGWGTVTS PQENFPNTLN CAEVKIYSQN KCERAYPGKI TEGMVCAGSS NGADTCQGDS GGPLVCDGML QGITSWGSDP CGKPEKPGVY TKICRYTTWI KKTMDNRD. It is sometimes possible for the material contained within the vial of "Kallikrein-8 (Klk8), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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