SDS-Page
KIM-1 recombinant protein
Recombinant Human KIM-1 (C-6His)
Purity
>95% as determined by reducing SDS-PAGE
Synonyms
KIM-1; Recombinant Human KIM-1 (C-6His); HAVCR1; HAVCR; HAVCR-1; KIM1; TIM; TIM-1; TIM1; TIMD-1; TIMD1; Hepatitis A viruscellular receptor 1; KIM-1 recombinant protein
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE
Form/Format
Supplied as a 0.2um filtered solution of PBS, pH7.4,5% Trehalose
Sequence
Ser21-Gly290
Species
Human
Tag
C-6His
Endotoxin
Please contact us for more information.
Protein Construction
Recombinant Human KIM-1 is produced by Mammalian expression system and the target gene encoding Ser21-Gly290 is expressed with a 6His tag at the C-terminus
Preparation and Storage
Store at < -20 degree C, stable for 6 months. Please minimize freeze-thaw cycles.
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20 degree C.
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20 degree C.
SDS-Page
SDS-Page
Related Product Information for KIM-1 recombinant protein
Kidney injury molecule-1 (KIM-1)(also known as TIM-1 and HAVCR) is a type 1 transmembrane glycoprotein found on activated CD4+ T cells, especially Th2 cells, and dedifferentiated proximal tubule epithelial cells. In humans, KIM-1 levels are very low or undetectable in normal samples, but following drug toxicity or ischemic damage to the kidney, the 85 kD, mucin-rich extracellular region of this molecule is shed and detected at elevated levels in urine, serum, and plasma. Therefore, KIM-1 is a suitable renal biomarker capable of early detection and progressive monitoring of acute kidney injury beyond traditional injury markers such as serum creatinine (SCr) and blood urea nitrogen (BUN) which lack specificity and sensitivity. KIM-1 has also been implicated in the development of atopic airway disease (asthma) and Th2-biased autoimmune responses.
NCBI and Uniprot Product Information
UniProt Accession #
Molecular Weight
Mol. Mass: 29.8kDa
AP Mol. Mass: 80-120kDa
AP Mol. Mass: 80-120kDa
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Product Notes
The KIM-1 (Catalog #AAA2569005) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Ser21-Gly2 90. It is sometimes possible for the material contained within the vial of "KIM-1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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