Mouse lysine (K) -specific demethylase 4C ELISA Kit | KDM4C elisa kit
Mouse Lysine-specific demethylase 4C, KDM4C ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
JMJD2C: the histone demethylase implicated in the epigenetic reprogramming during the early embryogenesis. Preferentially expressed in undifferentiated ES cells. JMJD2C, along with JMJD1A, regulate self-renewal in embryonic stem cells. Specifically demethylates 'Lys- 9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Two isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.14.11.-; Demethylase; Oxidoreductase
Cellular Component: nuclear chromatin; nucleus
Molecular Function: procollagen-proline dioxygenase activity; 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity; enzyme binding; histone demethylase activity; androgen receptor binding; dioxygenase activity; sulfonate dioxygenase activity; zinc ion binding; metal ion binding; DNA-N1-methyladenine dioxygenase activity; chromatin binding; oxidoreductase activity; histone demethylase activity (H3-K9 specific)
Biological Process: regulation of transcription from RNA polymerase II promoter; histone H3-K9 demethylation; transcription, DNA-dependent; regulation of transcription, DNA-dependent; regulation of gene expression; positive regulation of cell proliferation; blastocyst formation; chromatin modification; positive regulation of neuron differentiation
Research Articles on KDM4C
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Product Notes
The Mouse KDM4C kdm4c (Catalog #AAA9321688) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9321688 ELISA Kit recognizes Mouse KDM4C. It is sometimes possible for the material contained within the vial of "lysine (K) -specific demethylase 4C, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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