Western Blot (WB)
()
Rabbit DJ1 Polyclonal Antibody | anti-DJ1 antibody
DJ1 antibody
Applications
Western Blot
Purity
DJ1 antibody was purified by affinity chromatography
Synonyms
DJ1; Polyclonal Antibody; DJ1 antibody; Polyclonal DJ1; Anti-DJ1; PARK7; parkinson protein 7; BOS_15809; CAP1; contraception-associated protein 1; CTA-215D11.1; Dj1; DJ-1; DJ-1 protein; fertility protein SP22; oncogene DJ1; park7a; Parkinson disease 7; Parkinson disease (autosomal recessive; early onset) 7; early onset) 7 a; parkinson disease protein 7 homolog; protein DJ-1; protein DJ-1-like; putative Parkinson disease autosomal recessive early onset 7 variant 1; RNA-binding protein regulatory subunit; RP23-272N19.5; SP22; TEgg028p24.1; zDJ-1; anti-DJ1 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
DJ1 antibody was purified by affinity chromatography
Form/Format
Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol
Sequence Length
378
Applicable Applications for anti-DJ1 antibody
Western Blot (WB)
Application Notes
WB: 1:2000-5000
Biological Significance
Parkinson?s disease (PD) is the second most common neurodegenerative disorder after Alzheimer?s disease, with a prevalence of 1?2% in population aged 65 years or older. PD is a complex, multifactorial disorder that typically manifests after the age of 50 years. The pathology involves the loss of dopaminergic neurons in the substantia nigra and the presence of Lewy bodies (intraneuronal accumulations of aggregated proteins), in surviving neurons in various areas of the brain. alpha-synuclein and parkin are thought to be firmly associated with PD. The exact biological function of the DJ-1 protein is currently unknown. It may play a role in the oxidative stress response, and this function could be important in preventing the onset of PD. Defects in PARK7 are the cause of autosomal recessive early-onset Parkinson disease 7 (PARK7). The human DJ-1 protein contains 189 amino acid residues. DJ-1 may possess an active site and could also be a protease/hydrolase similar to the PfpI proteases. The DJ-1 gene has been highly conserved in evolution. The structures of the mouse and human DJ-1 genes are similar, and human and mouse DJ-1 proteins display 90% amino acid identity.
Cross-Reactivity
Human, Mouse, Rat
Immunogen
DJ1 antibody was raised in Rabbit using a recombinant human protein purified from E Coli (HIS-DJ-1) as the immunogen
Preparation and Storage
Aliquot and store for 1 year at -20 degree C, avoid freeze/thaw cycles
Western Blot (WB)
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Western Blot (WB)
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Related Product Information for anti-DJ1 antibody
Rabbit polyclonal DJ1 antibody
Product Categories/Family for anti-DJ1 antibody
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
40,597 Da
NCBI Official Full Name
DJ1
UniProt Protein Name
DJ1
UniProt Gene Name
dj1
UniProt Entry Name
D1MJ50_CRYPA
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Product Notes
The DJ1 dj1 (Catalog #AAA837334) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's DJ1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:2000-5000. Researchers should empirically determine the suitability of the DJ1 dj1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DJ1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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