Lysine-specific demethylase 3A (KDM3A) Recombinant Protein | KDM3A recombinant protein

Recombinant Human Lysine-specific demethylase 3A (KDM3A) , partial

• Gene Names: KDM3A; TSGA; JMJD1; JHDM2A; JHMD2A; JMJD1A
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Lysine-specific demethylase 3A (KDM3A); Recombinant Human Lysine-specific demethylase 3A (KDM3A); partial; KDM3A recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 1,321

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for KDM3A recombinant protein

This gene encodes a zinc finger protein that contains a jumonji domain and may play a role in hormone-dependent transcriptional activation. Alternative splicing results in multiple transcript variants.

NCBI and Uniprot Product Information

• NCBI GI #: 226442779
• NCBI GeneID: 55818
• NCBI Accession #: NP_001140160.1
• NCBI GenBank Nucleotide #: NM_001146688.1
• UniProt Accession #: Q9Y4C1; Q53S72; Q68D47; Q68UT9; Q6N050; Q8IY08; D6W5M3
• Molecular Weight: 147,341 Da
• NCBI Official Full Name: lysine-specific demethylase 3A
• NCBI Official Synonym Full Names: lysine demethylase 3A
• NCBI Official Symbol: KDM3A
• NCBI Official Synonym Symbols: TSGA; JMJD1; JHDM2A; JHMD2A; JMJD1A
• NCBI Protein Information: lysine-specific demethylase 3A
• UniProt Protein Name: Lysine-specific demethylase 3A
• Protein Family: Lysine-specific demethylase
• UniProt Gene Name: KDM3A
• UniProt Synonym Gene Names: JHDM2A; JMJD1; JMJD1A; KIAA0742; TSGA

NCBI Description

This gene encodes a zinc finger protein that contains a jumonji domain and may play a role in hormone-dependent transcriptional activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

Uniprot Description

Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. Involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation. Involved in spermatogenesis by regulating expression of target genes such as PRM1 and TNP1 which are required for packaging and condensation of sperm chromatin. Involved in obesity resistance through regulation of metabolic genes such as PPARA and UCP1.