Testing Data
(KDM3A antibody at 1/2000 dilution interacts with recombinant KDM3A protein with a His tag. Predicted band size: 48KDa. Observed band size: 48KDa.)
anti-Human KDM3A Antibody | anti-KDM3A antibody
KDM3A Antibody
WB: 1:100-1:2000
Testing Data
(KDM3A antibody at 1/2000 dilution interacts with recombinant KDM3A protein with a His tag. Predicted band size: 48KDa. Observed band size: 48KDa.)
Testing Data
(KDM3A antibody at 1/2000 dilution interacts with recombinant KDM3A protein with a His tag. Predicted band size: 48KDa. Observed band size: 48KDa.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a zinc finger protein that contains a jumonji domain and may play a role in hormone-dependent transcriptional activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Uniprot Description
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. Involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation. Involved in spermatogenesis by regulating expression of target genes such as PRM1 and TNP1 which are required for packaging and condensation of sperm chromatin. Involved in obesity resistance through regulation of metabolic genes such as PPARA and UCP1.
Research Articles on KDM3A
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Product Notes
The KDM3A kdm3a (Catalog #AAA850575) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The KDM3A Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KDM3A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:5000-1:20000 WB: 1:100-1:2000. Researchers should empirically determine the suitability of the KDM3A kdm3a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KDM3A, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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