Potassium channel subfamily K member 16 (KCNK16) Recombinant Protein | KCNK16 recombinant protein

Recombinant Human Potassium channel subfamily K member 16 (KCNK16)

Cat. Num. AAA7017737

• Gene Names: KCNK16; TALK1; TALK-1; K2p16.1
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Potassium channel subfamily K member 16 (KCNK16); Recombinant Human Potassium channel subfamily K member 16 (KCNK16); KCNK16 recombinant protein

• Host: Cell Free Expression
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Liquid containing glycerol
• Sequence Positions: 1-309. Full Length
• Sequence: MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWLALILPLGPLLLHRCCQLWLLSLRQGCGAKAAPGRRPRRGSTAARGVQVTPQDFPISKKGLGS

• Application Notes: This is a recombinant transmembrane protein expressed in a cell-free expression system.
• Species: Human
• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.; Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.

Product Categories/Family for KCNK16 recombinant protein

Transmembrane Protein

NCBI and Uniprot Product Information

• NCBI GI #: 205360971
• NCBI GeneID: 83795
• NCBI Accession #: NP_001128577.1
• NCBI GenBank Nucleotide #: NM_001135105.1
• UniProt Accession #: Q96T55; Q2M2N9; Q5TCF3; Q6X6Z3; Q6X6Z4; Q6X6Z5; Q9H591; B5TJL9
• Molecular Weight: 28,828 Da
• NCBI Official Full Name: potassium channel subfamily K member 16 isoform 1
• NCBI Official Synonym Full Names: potassium two pore domain channel subfamily K member 16
• NCBI Official Symbol: KCNK16
• NCBI Official Synonym Symbols: TALK1; TALK-1; K2p16.1
• NCBI Protein Information: potassium channel subfamily K member 16
• UniProt Protein Name: Potassium channel subfamily K member 16
• Protein Family: Potassium channel subfamily
• UniProt Gene Name: KCNK16
• UniProt Synonym Gene Names: TALK1; TALK-1
• UniProt Entry Name: KCNKG_HUMAN

NCBI Description

The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is expressed predominantly in the pancreas and is activated at alkaline pH. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2008]

Uniprot Description

KCNK16: Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents. Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6p21.2-p21.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: potassium channel activity; potassium ion leak channel activity; protein binding; voltage-gated ion channel activity

Biological Process: potassium ion transport; stabilization of membrane potential