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Human Potassium voltage-gated channel subfamily H member 7 ELISA Kit | KCNH7 elisa kit

Human Potassium voltage-gated channel subfamily H member 7 (KCNH7) ELISA Kit

Gene Names
KCNH7; ERG3; HERG3; Kv11.3
Reactivity
Human
Synonyms
Potassium voltage-gated channel subfamily H member 7; Human Potassium voltage-gated channel subfamily H member 7 (KCNH7) ELISA Kit; KCNH7 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
This assay has high sensitivity and excellent specificity for detection of Human KCNH7. No significant cross-reactivity or interference between Human KCNH7 and analogues was observed.
Sequence Length
732
Samples
Serum, Plasma, Other biological fluids
Assay Type
Sandwich
Sample Volume
1-200 uL
Precision
Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
Detection Wavelength
450 nm
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for KCNH7 elisa kit
Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate KCNH7 in samples. An antibody specific for KCNH7 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyKCNH7 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for KCNH7 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of KCNH7 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
82,904 Da
NCBI Official Full Name
potassium voltage-gated channel subfamily H member 7 isoform 1
NCBI Official Synonym Full Names
potassium voltage-gated channel subfamily H member 7
NCBI Official Symbol
KCNH7
NCBI Official Synonym Symbols
ERG3; HERG3; Kv11.3
NCBI Protein Information
potassium voltage-gated channel subfamily H member 7
UniProt Protein Name
Potassium voltage-gated channel subfamily H member 7
UniProt Gene Name
KCNH7
UniProt Synonym Gene Names
ERG3; ERG-3; Eag-related protein 3; Ether-a-go-go-related protein 3; hERG-3

NCBI Description

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

Kv11.3: Pore-forming (alpha) subunit of voltage-gated potassium channel. Channel properties may be modulated by cAMP and subunit assembly. Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.3/KCNH7 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, potassium; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 2q24.2

Cellular Component: integral component of plasma membrane; plasma membrane

Molecular Function: voltage-gated potassium channel activity

Biological Process: regulation of membrane potential

Research Articles on KCNH7

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Product Notes

The Human KCNH7 kcnh7 (Catalog #AAA280639) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA280639 ELISA Kit recognizes Human KCNH7. It is sometimes possible for the material contained within the vial of "Potassium voltage-gated channel subfamily H member 7, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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