Jun Dimerization Protein 2 Recombinant Protein | JDP2 recombinant protein
Recombinant Human Jun Dimerization Protein 2
Gene Names
JDP2; JUNDM2
Purity
Greater than 90.0% as determined by SDS-PAGE.
Synonyms
Jun Dimerization Protein 2; Recombinant Human Jun Dimerization Protein 2; JDP2 Human; Jun Dimerization Protein 2 Human Recombinant; Jun dimerization protein 2; JDP2; JUNDM2; Progesterone Receptor Co-Activator; JDP2 recombinant protein
Host
E Coli
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Form/Format
JDP2 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol, 1mM DTT, 1mM EDTA and 250mM imidazole.
Sterile Filtered colorless solution.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMMPGQI PDPSVTTGSL PGLGPLTGLP SSALTVEELK YADIRNLGAM IAPLHFLEVK LGKRPQPVKS ELDEEEERRK RRREKNKVAA ARCRNKKKER TEFLQRESER LELMNAELKT QIEELKQERQ QLILMLNRHR PTCIVRTDSV KTPESEGNPL LEQLEKK.
Sequence Length
163
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Related Product Information for JDP2 recombinant protein
Description: JDP2 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 187 amino acids (1-163 a.a) and having a molecular mass of 21.2kDa.JDP2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: Jun dimerization protein 2 (JDP2) is a component of the AP-1 transcription factor which inhibits transactivation mediated by the Jun family of proteins. JDP2 is involved in various transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. In addition, JDP2 can act as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. JDP2 controls transcription via direct regulation of the modification of histones and the assembly of chromatin.
Introduction: Jun dimerization protein 2 (JDP2) is a component of the AP-1 transcription factor which inhibits transactivation mediated by the Jun family of proteins. JDP2 is involved in various transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. In addition, JDP2 can act as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. JDP2 controls transcription via direct regulation of the modification of histones and the assembly of chromatin.
Product Categories/Family for JDP2 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
19,783 Da
NCBI Official Full Name
jun dimerization protein 2 isoform a
NCBI Official Synonym Full Names
Jun dimerization protein 2
NCBI Official Symbol
JDP2
NCBI Official Synonym Symbols
JUNDM2
NCBI Protein Information
jun dimerization protein 2; progesterone receptor co-activator
UniProt Protein Name
Jun dimerization protein 2
Protein Family
UniProt Gene Name
JDP2
UniProt Entry Name
JDP2_HUMAN
Uniprot Description
JDP2: a transcriptional coregulator that may play a role in progesterone receptor signaling. a JDP-2 lacks an intrinsic activation domain and interacts directly with other coactivators including CBP and pCAF.
Protein type: Transcription, coactivator/corepressor; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 14q24.3
Cellular Component: nucleoplasm; nucleus
Molecular Function: protein binding; sequence-specific DNA binding; protein heterodimerization activity; double-stranded DNA binding; chromatin binding; transcription factor activity
Biological Process: positive regulation of histone deacetylation; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; negative regulation of fat cell differentiation
Research Articles on JDP2
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Product Notes
The JDP2 jdp2 (Catalog #AAA145866) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSHMM PGQI PDPSVTTGSL PGLGPLTGLP SSALTVEELK YADIRNLGAM IAPLHFLEVK LGKRPQPVKS ELDEEEERRK RRREKNKVAA ARCRNKKKER TEFLQRESER LELMNAELKT QIEELKQERQ QLILMLNRHR PTCIVRTDSV KTPESEGNPL LEQLEKK.. It is sometimes possible for the material contained within the vial of "Jun Dimerization Protein 2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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