Human jumonji, AT rich interactive domain 1D ELISA Kit | JARID1D elisa kit
Human Lysine-specific demethylase 5D, JARID1D ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein containing zinc finger domains. A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Uniprot Description
JARID1D: Histone demethylase that specifically demethylates 'Lys- 4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis. Belongs to the JARID1 histone demethylase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Oxidoreductase; EC 1.14.11.-
Chromosomal Location of Human Ortholog: Yq11
Cellular Component: nucleoplasm
Molecular Function: histone demethylase activity (H3-K4 specific); DNA binding; zinc ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
Biological Process: establishment and/or maintenance of chromatin architecture
Disease: Spermatogenic Failure, Y-linked, 2
Research Articles on JARID1D
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Product Notes
The Human JARID1D kdm5d (Catalog #AAA9329753) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9329753 ELISA Kit recognizes Human JARID1D. It is sometimes possible for the material contained within the vial of "jumonji, AT rich interactive domain 1D, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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