Intersectin-1 (Itsn1) Recombinant Protein | Itsn1 recombinant protein

Recombinant Rat Intersectin-1 (Itsn1) , partial

• Gene Names: Itsn1; Itsn; EHSH1
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Intersectin-1 (Itsn1); Recombinant Rat Intersectin-1 (Itsn1); partial; Itsn1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 1217

• Species: Rat
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for Itsn1 recombinant protein

This protein is a cytoplasmic membrane-associated protein that indirectly coordinates endocytic membrane traffic with the actin assembly machinery. In addition, the encoded protein may regulate the formation of clathrin-coated vesicles and could be involved in synaptic vesicle recycling. This protein has been shown to interact with dynamin, CDC42, SNAP23, SNAP25, SPIN90, EPS15, EPN1, EPN2, and STN2. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been characterized so far.

NCBI and Uniprot Product Information

• NCBI GI #: 9506823
• NCBI GeneID: 29491
• NCBI Accession #: NP_062100.1
• NCBI GenBank Nucleotide #: NM_019227.1
• UniProt Accession #: Q9WVE9; Q9WVE1
• Molecular Weight: 129,443 Da
• NCBI Official Full Name: intersectin-1 isoform b
• NCBI Official Synonym Full Names: intersectin 1
• NCBI Official Symbol: Itsn1
• NCBI Official Synonym Symbols: Itsn; EHSH1
• NCBI Protein Information: intersectin-1
• UniProt Protein Name: Intersectin-1
• Protein Family: Intersectin
• UniProt Gene Name: Itsn1
• UniProt Synonym Gene Names: Ehsh1; Itsn

NCBI Description

binds to dynamin and SNAP-25; may be involved in exocytosis [RGD, Feb 2006]

Uniprot Description

Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles. Inhibits ARHGAP31 activity toward RAC1.