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SDS-Page

IPP-POZ domain Recombinant Protein | IPP-POZ recombinant protein

IPP-POZ domain, 1-157aa, Human E Coli

Gene Names
IPP; KLHL27
Applications
SDS-Page
Purity
> 95% by SDS-PAGE
Synonyms
IPP-POZ domain; 1-157aa; Human E Coli; Intracisternal A particle-promoted polypeptide isoform 1; IPP; KLHL27; MIPP protein; Kelch-like protein 27; Actin-binding protein IPP; Protein phosphatase inhibitor 1; Actin binding protein IPP; I1; Intracisternal A particle promoted polypeptide; IPP POZ; Kelch like protein 27; Protein phosphatase 1 regulatory subunit 1A; IPP-POZ recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid. In 10 mM HEPES (pH 7.4), 25mM NaCl
Concentration
1 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MANEDCPKAA DSPFSSDKHA QLILAQINKM RNGQHFCDVQ LQVGQESFKA HRLVLAASSP YFAALFTGGM KESSKDVVPI LGIEAGIFQI LLDFIYTGIV NIGVNNVQEL IIAADMLQLT EVVHLCCEFL KGQIDPLNCI GIFQFSEQIA CHDLLEF
Sequence Length
584
Applicable Applications for IPP-POZ recombinant protein
SDS-PAGE
Antigen Species
Human
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

SDS-Page

SDS-Page
Related Product Information for IPP-POZ recombinant protein
Intracisternal A particle-promoted polypeptide (IPP) is a 66kDa protein (584 amino acids), which contains an N-terminal POZ protein-protein interaction domain and a C-terminla kelch repeat domain consisting of six tandem arranged repeats. The POZ domain (also called BTB domain) is present near the N-terminus of a fraction of zinc finger proteins and in protein that contain the pfam01344 motif such as kelch and pox virus proteins. The BTB/POZ domain mediates homomeric dimerization and in some instances heteromeric dimerization. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-coR and SMRT. IPP-POZ domain (1-157aa) was overexpressed in E Coli and purified by using conventional chromatography techniques
Product Categories/Family for IPP-POZ recombinant protein
References
Kim IF., et al. (1999) Gene 228 (1-2), 73-83.; Chang-Yeh, A., et al. (1993) Genomics. 15 (1), 239-241.;

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
17.3 kDa (157 aa), confirmed by MALDI-TOF.
NCBI Official Full Name
actin-binding protein IPP isoform 1
NCBI Official Synonym Full Names
intracisternal A particle-promoted polypeptide
NCBI Official Symbol
IPP
NCBI Official Synonym Symbols
KLHL27
NCBI Protein Information
actin-binding protein IPP
UniProt Protein Name
Actin-binding protein IPP
UniProt Gene Name
IPP
UniProt Synonym Gene Names
KLHL27; IPP

NCBI Description

The protein encoded by this gene is a member of the kelch family of proteins, which is characterized by a 50 amino acid repeat which interacts with actin. Transcript variants have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

May play a role in organizing the actin cytoskeleton.

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Product Notes

The IPP-POZ ipp (Catalog #AAA203062) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IPP-POZ domain can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the IPP-POZ ipp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MANEDCPKAA DSPFSSDKHA QLILAQINKM RNGQHFCDVQ LQVGQESFKA HRLVLAASSP YFAALFTGGM KESSKDVVPI LGIEAGIFQI LLDFIYTGIV NIGVNNVQEL IIAADMLQLT EVVHLCCEFL KGQIDPLNCI GIFQFSEQIA CHDLLEF. It is sometimes possible for the material contained within the vial of "IPP-POZ domain, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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