Type I inositol 1,4,5-trisphosphate 5-phosphatase CVP2 (CVP2) Recombinant Protein | CVP2 recombinant protein

Recombinant Arabidopsis thaliana Type I inositol 1,4,5-trisphosphate 5-phosphatase CVP2 (CVP2) , partial

• Gene Names: CVP2; COTYLEDON VASCULAR PATTERN 2; T25N20.12; T25N20_12
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Type I inositol 1; 4; 5-trisphosphate 5-phosphatase CVP2 (CVP2); Recombinant Arabidopsis thaliana Type I inositol 1; partial; CVP2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 506

• Species: Arabidopsis thaliana (Mouse-ear cress)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 1063680525
• NCBI GeneID: 837048
• NCBI Accession #: NP_001322092.1
• NCBI GenBank Nucleotide #: NM_001331550.1
• UniProt Accession #: Q9LR47
• Molecular Weight: 57,931 Da
• NCBI Official Full Name: DNAse I-like superfamily protein
• NCBI Official Symbol: CVP2
• NCBI Official Synonym Symbols: COTYLEDON VASCULAR PATTERN 2; T25N20.12; T25N20_12
• NCBI Protein Information: DNAse I-like superfamily protein
• UniProt Protein Name: Type IV inositol polyphosphate 5-phosphatase 6
• UniProt Gene Name: IP5P6
• UniProt Synonym Gene Names: At5PTase6Curated

NCBI Description

Encodes an inositol polyphosphate 5' phosphatase (5PTase) that is required for the proper recruitment of cells into developing vascular tissue in leaves and cotyledons. It is most similar to Type I 5PTases that are known to cleave a phosphate from IP3 or IP4. cvp2 mutants have elevated levels of IP3 and are hypersensitive to ABA in seed germination assays.

Uniprot Description

Has phosphatase activity toward PtdIns(4,5)P2 and PtdIns(3,4,5)P3 (PubMed:19473324). Required for the patterning of procambium and during the differentiation of vascular tissues. Acts before the acquisition of preprocambial identity. Seems to be also involved in the abscisic acid (ABA) signaling pathway (PubMed:10559439, PubMed:15100402). Acts redundantly with CVL1 for maintaining vascular continuity (PubMed:19363154, PubMed:25813544). Regulates phosphoinositide-dependent VAN3 localization (PubMed:19473324).