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Human Cross-linked N-terminal telopeptide of Collagen alpha-1 (I) chain ELISA Kit | INTX elisa kit

Human Cross-linked N-terminal telopeptide of Collagen alpha-1 (I) chain ELISA Kit

Gene Names
COL1A1; OI1; OI2; OI3; OI4; EDSC
Reactivity
Human
Synonyms
Cross-linked N-terminal telopeptide of Collagen alpha-1 (I) chain; Human Cross-linked N-terminal telopeptide of Collagen alpha-1 (I) chain ELISA Kit; INTX; INTX elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Samples
Serum, plasma, tissue homogenates and other biological fluids.
Detection Range
0.312-20 ng/mL
Sensitivity
Less than 0.21ng/mL
Assay Time
3-5h
Sample Volume
100T
Detection Wavelength
450 nm
Preparation and Storage
Store at 4 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
138,941 Da
NCBI Official Full Name
collagen alpha-1(I) chain preproprotein
NCBI Official Synonym Full Names
collagen type I alpha 1 chain
NCBI Official Symbol
COL1A1
NCBI Official Synonym Symbols
OI1; OI2; OI3; OI4; EDSC
NCBI Protein Information
collagen alpha-1(I) chain
UniProt Protein Name
Collagen alpha-1(I) chain
UniProt Gene Name
COL1A1

NCBI Description

This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]

Uniprot Description

Type I collagen is a member of group I collagen (fibrillar forming collagen).

Research Articles on INTX

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Product Notes

The Human INTX col1a1 (Catalog #AAA9425919) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9425919 ELISA Kit recognizes Human INTX. It is sometimes possible for the material contained within the vial of "Cross-linked N-terminal telopeptide of Collagen alpha-1 (I) chain, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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