Protein inturned (INTU) Recombinant Protein | INTU recombinant protein

Recombinant Bovine Protein inturned (INTU) , partial

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Protein inturned (INTU); Recombinant Bovine Protein inturned (INTU); partial; INTU recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 933

• Species: Bovine
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 329663515
• NCBI GeneID: 519372
• NCBI Accession #: NP_001192784.1
• NCBI GenBank Nucleotide #: NM_001205855.1
• UniProt Accession #: F1MDL2
• Molecular Weight: 104,454 Da
• NCBI Official Full Name: protein inturned
• NCBI Official Synonym Full Names: inturned planar cell polarity protein
• NCBI Official Symbol: INTU
• NCBI Protein Information: protein inturned
• UniProt Protein Name: Protein inturned
• UniProt Gene Name: INTU
• UniProt Synonym Gene Names: PDZD6

Uniprot Description

Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies ().