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Western Blot (WB) (mouse liver tissue were subjected to SDS PAGE followed by western blot with MBS7600600 (INTU Antibody) at dilution of 1:1000)

Rabbit anti-Human, Mouse INTU Polyclonal Antibody | anti-INTU antibody

INTU Rabbit Polyclonal

Gene Names
INTU; INT; PDZD6; PDZK6
Reactivity
Human, Mouse
Applications
ELISA, Western Blot
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
INTU; Polyclonal Antibody; INTU Rabbit Polyclonal; anti-INTU antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
408
Applicable Applications for anti-INTU antibody
ELISA (EIA), Western Blot (WB)
Immunogen
Inturned planar cell polarity effector homolog (Drosophila)
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Western Blot (WB)

(mouse liver tissue were subjected to SDS PAGE followed by western blot with MBS7600600 (INTU Antibody) at dilution of 1:1000)

Western Blot (WB) (mouse liver tissue were subjected to SDS PAGE followed by western blot with MBS7600600 (INTU Antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
103,737 Da
NCBI Official Full Name
INTU protein
NCBI Official Synonym Full Names
inturned planar cell polarity protein
NCBI Official Symbol
INTU
NCBI Official Synonym Symbols
INT; PDZD6; PDZK6
NCBI Protein Information
protein inturned
UniProt Protein Name
Protein inturned
UniProt Gene Name
INTU
UniProt Synonym Gene Names
KIAA1284; PDZD6; PDZK6
UniProt Entry Name
INTU_HUMAN

Uniprot Description

INTU: Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling. Belongs to the inturned family. 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 4q28.1

Cellular Component: cell surface; cytoplasm

Biological Process: cilium biogenesis; embryonic digit morphogenesis; hair follicle morphogenesis; keratinocyte differentiation; limb development; negative regulation of cell division; nervous system development; neural tube development; positive regulation of smoothened signaling pathway; regulation of ossification; regulation of smoothened signaling pathway; spinal cord dorsal/ventral patterning

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Product Notes

The INTU intu (Catalog #AAA7600600) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The INTU Rabbit Polyclonal reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's INTU can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the INTU intu for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "INTU, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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