SDS-Page
(Human IFNA5 / IFNaG Protein (His Tag))
interferon-alpha/IFNA5 Recombinant Protein | IFNA5 recombinant protein
interferon-alpha/IFNA5 Protein, Human, Recombinant (His Tag)
Gene Names
IFNA5; INA5; INFA5; leIF G; IFN-alphaG; IFN-alpha-5
Purity
>90% as determined by SDS-PAGE
Synonyms
interferon-alpha/IFNA5; interferon-alpha/IFNA5 Protein; Human; Recombinant (His Tag); Human IFNA5/IFNaG Protein (His Tag); IFN-alpha Protein; IFN-alpha-5 Protein; IFN-alphaG Protein; INA5 Protein; INFA5 Protein; leIF G Protein; RP11-380P16.5 Protein; interferon; alpha 5; IFNA5 recombinant protein
Host
Yeast
Purity/Purification
>90% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Leu22-Glu189
Species
Human
Predicted N Terminal
Leu 22
Tag
C-His
Protein Construction
A DNA sequence encoding the human IFNA5 (NP_002160.1)(Leu22-Glu189) was expressed with a polyhistidine tag at the C-terminus.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
SDS-Page
(Human IFNA5 / IFNaG Protein (His Tag))
SDS-Page
(Human IFNA5 / IFNaG Protein (His Tag))
Related Product Information for IFNA5 recombinant protein
Background: Interferon, alpha 5 (IFNA5) belongs to the alpha/beta interferon family. IFNA5 is the only IFNA subtype detected in normal liver, while a mixture of subtypes is observed in the liver tissue of patients with chronic hepatitis C. Interferons are produced by macrophages, IFN-alpha has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha, the first cytokine to be produced by recombinant DNA technology, has emerged as an important regulator of growth and differentiation, affecting cellular communication and signal transduction pathways as well as immunological control. Originally discovered as an antiviral substance, the efficacy of IFN-alpha in malignant, viral, immunological, angiogenic, inflammatory, and fibrotic diseases suggests a spectrum of interrelated pathophysiologies. IFN-alpha emerged as a prototypic tumor suppressor protein that represses the clinical tumorigenic phenotype in some malignancies capable of differentiation.
References
Lau JY, et al. (1993) Discrepancy between biochemical and virological responses to interferon-alpha in chronic hepatitis C. Lancet. 342(8881): 1208-9.Kessler DS, et al. (1990) Interferon-alpha regulates nuclear translocation and DNA-binding affinity of ISGF3, a multimeric transcriptional activator. Genes Dev. 4(10): 1753-65.Gutterman JU. Cytokine therapeutics: lessons from interferon alpha. Proc Natl Acad Sci U S A. 91(4): 1198-205.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21,942 Da
NCBI Official Full Name
interferon alpha-5
NCBI Official Synonym Full Names
interferon, alpha 5
NCBI Official Symbol
IFNA5
NCBI Official Synonym Symbols
INA5; INFA5; leIF G; IFN-alphaG; IFN-alpha-5
NCBI Protein Information
interferon alpha-5; interferon alpha-G; interferon alpha-61
Protein Family
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Product Notes
The IFNA5 (Catalog #AAA8120210) is a Recombinant Protein produced from Yeast and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Leu22-Glu1 89. It is sometimes possible for the material contained within the vial of "interferon-alpha/IFNA5, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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