Interferon alpha 10/IFNA10 Recombinant Protein | IFNA10 recombinant protein

Interferon alpha 10/IFNA10 Protein, Human, Recombinant (His Tag)

Cat. Num. AAA8120220

• Gene Names: IFNA10; IFN-alphaC
• Purity: >95% as determined by SDS-PAGE
• Synonyms: Interferon alpha 10/IFNA10; Interferon alpha 10/IFNA10 Protein; Human; Recombinant (His Tag); Human IFNA10 Protein (His Tag); IFN-alphaC Protein; MGC119878 Protein; MGC119879 Protein; interferon; alpha 10; IFNA10 recombinant protein

• Host: HEK293 Cells
• Purity/Purification: >95% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Met1-Asp189

• Species: Human
• Endotoxin: <1.0EU per ug protein as determined by the LAL method.
• Predicted N Terminal: Cys 24
• Tag: C-His
• Protein Construction: A DNA sequence encoding the human IFNA10 (NP_002162.1)(Met1-Asp189) was expressed with a polyhistidine tag at the C-terminus.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

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Related Product Information for IFNA10 recombinant protein

Background: Interferon alpha-10 (IFNA10) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a consequence of the cause answer by different inductors. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs have other functions: they activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes, and they increase the ability of uninfected host cells to resist new infection by the virus. Certain host symptoms, such as aching muscles and fever, are related to the production of IFNs during infection. Human IFNs are divided on the sequence of amino-acids into three groups: Alpha, Beta, and Gamma interferons.

References

De Veer MJ, et al. (2001) Functional classification of interferon-stimulated genes identified using microarrays. J Leukoc Biol. 69 (6): 912-20.Liu YJ. (2005) IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. Annu Rev Immunol. 23: 275-306.Fensterl V, et al. (2009) Interferons and viral infections. Biofactors. 35 (1): 14-20.

NCBI and Uniprot Product Information

• NCBI GI #: 4504589
• NCBI GeneID: 3446
• NCBI Accession #: NP_002162.1
• NCBI GenBank Nucleotide #: NM_002171.2
• Molecular Weight: 21,835 Da
• NCBI Official Full Name: interferon alpha-10
• NCBI Official Synonym Full Names: interferon, alpha 10
• NCBI Official Symbol: IFNA10
• NCBI Official Synonym Symbols: IFN-alphaC
• NCBI Protein Information: interferon alpha-10; leIF C; IFN-alpha-10; interferon alpha-C; interferon alpha-6L
• Protein Family: Interferon