Human insulinoma-associated 1 ELISA Kit | INSM1 elisa kit

Human Insulinoma-associated protein 1, INSM1 ELISA Kit

Cat. Num. AAA9327435

• Gene Names: INSM1; IA1; IA-1
• Reactivity: Human
• Synonyms: insulinoma-associated 1; Human Insulinoma-associated protein 1; INSM1 ELISA Kit; Human Insulinoma-associated protein 1 (INSM1) ELISA kit; IA-1; IA1; ; INSM1 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: undiluted original Human body fluids, tissue homogenates, secretions or feces samples
• Assay Type: Quantitative Sandwich
• Detection Range: 3.12ng/ml-100ng/mL
• Sensitivity: 1.0ng/mL
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for INSM1 elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of INSM1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 4504713
• NCBI GeneID: 3642
• NCBI Accession #: NP_002187.1
• NCBI GenBank Nucleotide #: NM_002196.2
• UniProt Accession #: Q01101
• Molecular Weight: 52,923 Da
• NCBI Official Full Name: insulinoma-associated protein 1
• NCBI Official Synonym Full Names: insulinoma-associated 1
• NCBI Official Symbol: INSM1
• NCBI Official Synonym Symbols: IA1; IA-1
• NCBI Protein Information: insulinoma-associated protein 1; zinc finger protein IA-1
• UniProt Protein Name: Insulinoma-associated protein 1
• Protein Family: Insulinoma-associated protein
• UniProt Gene Name: INSM1
• UniProt Synonym Gene Names: IA1
• UniProt Entry Name: INSM1_HUMAN

NCBI Description

Insulinoma-associated 1 (INSM1) gene is intronless and encodes a protein containing both a zinc finger DNA-binding domain and a putative prohormone domain. This gene is a sensitive marker for neuroendocrine differentiation of human lung tumors. [provided by RefSeq, Jul 2008]

Uniprot Description

INSM1: May be associated with the transformation of neuroendocrine cells.

Protein type: C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 20p11.2

Cellular Component: nucleoplasm; transcriptional repressor complex; nucleus

Molecular Function: cyclin binding; chromatin DNA binding; metal ion binding; histone deacetylase binding; transcription factor activity

Biological Process: norepinephrine biosynthetic process; negative regulation of cell proliferation; negative regulation of protein amino acid phosphorylation; transcription, DNA-dependent; regulation of gene expression; regulation of protein complex assembly; negative regulation of transcription from RNA polymerase II promoter; cell cycle; positive regulation of cell differentiation; endocrine pancreas development