Testing Data
ST6GALNAC1 active protein
ST6GalNAc1, soluble fragment, Human Recombinant
Gene Names
ST6GALNAC1; STYI; SIAT7A; HSY11339; ST6GalNAcI
Purity
>90% by SDS-PAGE
Synonyms
ST6GalNAc1; soluble fragment; Human Recombinant; Beta-1; 4-galactosyltransferase 1; UDP-Gal:beta-GlcNAc beta-1; UDP-galactose:beta-N-acetylglucosamine beta-1; 4-GalTase 1; Beta4Gal-T1; ST6GALNAC1 active protein
Host
Insect cells
Purity/Purification
>90% by SDS-PAGE
Form/Format
Liquid. Sterile filtered solution in 20mM Hepes pH7 and 100mM NaCl
Concentration
500ug/ml (varies by lot)
Gene Source
Human
Biological Activity
Specific activity >50 pmol/min/mg
Measured by transfer of NeuAc from CMP-NeuAc to the Tn-peptide MEELGMAPALQPT (GalNAc) QGAMPAF.
Measured by transfer of NeuAc from CMP-NeuAc to the Tn-peptide MEELGMAPALQPT (GalNAc) QGAMPAF.
Preparation and Storage
Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months
Centrifuge the vial prior to opening.
Shelf life: ~12 months
Testing Data
Testing Data
Related Product Information for ST6GALNAC1 active protein
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 catalyzes the transfer of sialic acid N-acetylneuraminic acid (Neu5Ac) from cytidine 5'-monophosphono-N-acetylneuraminic acid (CMP-Neu5Ac) to O-linked GalNAc residues in an alpha-2,6 linkage. ST6GalNAcI belongs to a large family of Golgi-membrane-bound sialyltransferases that is responsible for the biosynthesis of sialyated structures, and from which approximately 20 have been cloned to date. The cancer associated sialyl-Tn (sTn) angtigen is formed by ST6GalNAcI, through the transfer of Neu5Ac to GalNAc resiudes on mucins. Addition of a sialic acid to a glyco-protein effectively caps the glycan-chain, preventing further additions. The presence of sialic acid residues extends the half-life of circulating proteins, and are considered to be important for a large variety of biotherapuetics.
Product Categories/Family for ST6GALNAC1 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
68,564 Da
NCBI Official Full Name
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 isoform 1
NCBI Official Synonym Full Names
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
NCBI Official Symbol
ST6GALNAC1
NCBI Official Synonym Symbols
STYI; SIAT7A; HSY11339; ST6GalNAcI
NCBI Protein Information
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; GalNAc alpha-2, 6-sialyltransferase I, long form; SIAT7-A; ST6GalNAc I; galNAc alpha-2,6-sialyltransferase I; sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl gal
UniProt Protein Name
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
Protein Family
UniProt Gene Name
ST6GALNAC1
UniProt Synonym Gene Names
SIAT7A; ST6GalNAcI; SIAT7-A
UniProt Entry Name
SIA7A_HUMAN
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Product Notes
The ST6GALNAC1 st6galnac1 (Catalog #AAA849850) is an Active Protein produced from Insect cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ST6GalNAc1, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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