Structure
YL0919, Inhibitor
YL0919
Purity
>98% (HPLC)
Synonyms
YL0919; YL-0919; YL 0919; inhibitor
Purity/Purification
>98% (HPLC)
Suitability
DMSO: >=30mg/mL
Target
5-HT Receptor
Receptor
5-HT; 5-HT1A
Chemical Name
2(1H)-Pyridinone, 1-[[4-hydroxy-1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride(1:1)
SMILES
O=C1C=CC=CN1CC2(O)CCN(CC3=CC=CC=C3)CC2.[H]Cl
Molecular Formula
C18H23ClN2O2
CAS Number
1339058-04-6
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for YL0919, inhibitor
An orally active, dual 5-HT1A agonist and selective serotonin reuptake inhibitor with Ki of 0.19nM and IC50 of 1.78nM, respectively; shows no affinity for dopamine receptors and others 5-HT receptors; inhibits forskolin-stimulated cAMP formation and 5-HT uptake in both rat cortical synaptosomes and recombinant cells; significantly reverses the depressive-like behaviors in chronically stressed rats.
Product Categories/Family for YL0919, inhibitor
References
1. Chen HX, et al. PLoS One. 2013 Dec 18; 8 (12):e83271.
2. Zhang LM, et al. Br J Pharmacol. 2017 May; 174 (9):769-780.
3. Qin JJ, et al. Neurosci Lett. 2014 Oct 17; 582:104-8.
2. Zhang LM, et al. Br J Pharmacol. 2017 May; 174 (9):769-780.
3. Qin JJ, et al. Neurosci Lett. 2014 Oct 17; 582:104-8.
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Product Notes
The YL0919 (Catalog #AAA3601363) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "YL0919, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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