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Structure

TDI-2760, Inhibitor

TDI-2760

Purity
>98% (HPLC)
Synonyms
TDI-2760; TDI2760; inhibitor
Ordering
Purity/Purification
>98% (HPLC)
Target
Amyloids
Receptor
Amyloids
Chemical Name
5-(3-(dimethylamino)phenoxy)-N-phenylpyrimidin-2-amine
Molecular Formula
C18H18N4O
CAS Number
956128-08-8
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Structure

Structure
Related Product Information for TDI-2760, inhibitor
TDI-2760 si a small molecule Abeta-aggregation inhibitor that not only shows a strong inhibitory efficacy toward the Abeta-fibrinogen interaction (IC50=1.67uM) but also retains potency toward the Abeta42 aggregation inhibition process; restores the Abeta42-induced decrease in fibrin clot turbidity without affecting normal clotting in an in vitro clotting assay, effectively inhibits Abeta42 fibrillization and modulates Abeta42-induced contact system activation.
Product Categories/Family for TDI-2760, inhibitor
References
1. Singh PK, et al. Biochemistry. 2018 Feb 27; 57 (8):1399-1409.

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Product Notes

The TDI-2760 (Catalog #AAA3606818) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "TDI-2760, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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