Talarozole, Inhibitor
Talarozole
Purity
>98% (HPLC)
Synonyms
Talarozole; R115866; inhibitor
Purity/Purification
>98% (HPLC)
Suitability
DMSO: 36mg/mL (95.36mM)
Target
Autophagy
Receptor
RAMBA; CYP
SMILES
CCC(CC)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1
Molecular Formula
C21H23N5S
CAS Number
201410-53-9
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Related Product Information for Talarozole, inhibitor
Talarozole is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46nM respectively.Talarozole for the treatment of acne psoriasis and other keratinization disorders.
References
1.Elizabeth Pavez Lorii¨ Chamcheu J C Vahlquist A et al. Both all-trans retinoic acid and cytochrome P450 (CYP26) inhibitors affect the expression of vitamin A metabolizing enzymes and retinoid biomarkers in organotypic epidermis [J]. Archives of Dermatological Research 2009 301 (7):475-485.
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Product Notes
The Talarozole (Catalog #AAA3610712) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Talarozole, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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