TA-01, inhibitor
TA-01
Purity
98.00%
Synonyms
TA-01; Casein Kinase; p38 MAPK; inhibitor
Purity/Purification
98.00%
Form/Format
POWDER
CAS Number
1784751-18-3
Formula
C20H12F3N3
Smiles
Fc1ccc(cc1)-c1nc([nH]c1-c1ccncc1)-c1c(F)cccc1F
Solubility
DMSO: 10 mM
Pathways
Metabolism; MAPK
Receptor
CK1epsilon; CK1delta; p38 MAPK
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
In Solvent: 2 years -80 degree C
Related Product Information for TA-01, inhibitor
TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1epsilon, CK1delta and p38 MAPK, respectively.
Product Categories/Family for TA-01, inhibitor
References
1. Laco F, et al. Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling. J Mol Cell Cardiol. 2015 Mar; 80:56-70.
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Product Notes
The TA-01 (Catalog #AAA5750721) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "TA-01, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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