T-705 (Favipiravir), Inhibitor

T-705 (Favipiravir)

Cat. Num. AAA386245

• Purity: >98%
• Synonyms: T-705 (Favipiravir); T705; T 705; inhibitor

• Purity/Purification: >98%
• Form/Format: Powder
• Concentration: 0.1 mM: 63.65 mL (1 mg); 318.27 mL (5 mg); 636.54mL (10 mg); 0.5 mM: 12.73 mL (1 mg); 63.65 mL (5 mg); 127.31 mL (10 mg); 1 mM: 6.37 mL (1 mg); 31.83 mL (5 mg); 63.65 mL (10 mg); 5 mM: 1.27 mL (1 mg); 6.37 mL (5 mg); 12.73 mL (10 mg) (varies by lot)

• CAS Number: 259793-96-9
• Formula: C5H4FN3O2
• SMILES: C1=C(N=C(C(=O)N1)C(=O)N)F
• Actions: Inhibitor
• Availability: We cannot ship this item to Switzerland, Italy, Germany, France and Austria.
• Preparation and Storage: at -20 degree C 3 years Powder

Chemical Structure

Related Product Information for T-705 (Favipiravir), inhibitor

T-705, a substituted pyrazine compound, has been found to exhibit potent anti-influenza virus activity in vitro and in vivo.

References

JE Comer, .et al. Filovirus Virulence in Interferon α,β and γ Double Knockout Mice, and Treatment with Favipiravir, Viruses, 2019, Feb 3;11(2). pii: E137 PMID: 30717492
Ma J, .et al. Enhancing the antiviral potency of ER α-glucosidase inhibitor IHVR-19029 against hemorrhagic fever viruses in vitro and in vivo, Antiviral Res, 2018, Feb;150:112-122 PMID: 29253498
Ji-Ae Kim, .et al. Favipiravir and Ribavirin Inhibit Replication of Asian and African Strains of Zika Virus in Different Cell Models, Viruses, 2018, Feb; 10(2): 72 PMID: 29425176
Haejin Chun, .et al. Efficient antiviral co-delivery using polymersomes by controlling the surface density of cell-targeting groups for influenza A virus treatment, Polym Chem, 2018, 9: 2116-2123
Baz M, .et al. Combination Therapy with Oseltamivir and Favipiravir Delays Mortality but Does Not Prevent Oseltamivir Resistance in Immunodeficient Mice Infected with Pandemic A(H1N1) Influenza Virus, Viruses, 2018, Nov 3;10(11) PMID: 30400276
Sehee Park, .et al. Combination Effects of Peramivir and Favipiravir against Oseltamivir-Resistant 2009 Pandemic Influenza A(H1N1) Infection in Mice, PLoS One., 2014, 9(7): e101325 PMID: 24992479