Chemical Structure
Retigabine (Ezogabine), Inhibitor
Retigabine (Ezogabine)
Purity
>98%
Synonyms
Retigabine (Ezogabine); inhibitor
Purity/Purification
>98%
Form/Format
Powder
Concentration
Concentration / Solvent Volume / Mass
0.1 mM: 32.97 mL (1 mg); 164.83 mL (5 mg); 329.66mL (10 mg)
0.5 mM: 6.59 mL (1 mg); 32.97 mL (5 mg); 65.93 mL (10 mg)
1 mM: 3.3 mL (1 mg); 16.48 mL (5 mg); 32.97 mL (10 mg)
5 mM: 0.66 mL (1 mg); 3.3 mL (varies by lot)
0.1 mM: 32.97 mL (1 mg); 164.83 mL (5 mg); 329.66mL (10 mg)
0.5 mM: 6.59 mL (1 mg); 32.97 mL (5 mg); 65.93 mL (10 mg)
1 mM: 3.3 mL (1 mg); 16.48 mL (5 mg); 32.97 mL (10 mg)
5 mM: 0.66 mL (1 mg); 3.3 mL (varies by lot)
CAS Number
150812-12-7
Formula
C16H18FN3O2
SMILES
CCOC(=O)NC1=C(C=C(C=C1)NCC2=CC=C(C=C2)F)N
Solubility
In vitro:
DMSO : 58 mg/mL (9191.21 mM)
Water: Insoluble
Ethanol : 34 mg/mL (112.08 mM)
*<1 mg/mL means slightly soluble or insoluble
*Please note that MBS386025 tests the solubility of all compunds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
DMSO : 58 mg/mL (9191.21 mM)
Water: Insoluble
Ethanol : 34 mg/mL (112.08 mM)
*<1 mg/mL means slightly soluble or insoluble
*Please note that MBS386025 tests the solubility of all compunds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Availability
We cannot ship this item to Switzerland, Italy, Germany, France and Austria.
Preparation and Storage
Store at -20 degree C 3 years Powder
Chemical Structure
Chemical Structure
Related Product Information for Retigabine (Ezogabine), inhibitor
Retigabine is an anticonvulsant used as a treatment for partial epilepsies.
References
Joseph Lombardo, .et al. Nonreciprocal mechanisms in up- and downregulation of spinal motoneuron excitability by modulators of KCNQ/Kv7 channels, J Neurophysiol, 2016, Nov 1; 116(5): 2114-2124 PMID: 27512022
Sonya M. Bierbower, .et al. Augmentation of M-Type (KCNQ) Potassium Channels as a Novel Strategy to Reduce Stroke-Induced Brain Injury, J Neurosci, 2015, Feb 4; 35(5): 2101-2111 PMID: 25653366
Sonya M. Bierbower, .et al. Augmentation of M-Type (KCNQ) Potassium Channels as a Novel Strategy to Reduce Stroke-Induced Brain Injury, J Neurosci, 2015, Feb 4; 35(5): 2101-2111 PMID: 25653366
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Product Notes
The Retigabine (Ezogabine) (Catalog #AAA386025) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Retigabine (Ezogabine), Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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