Structure
Quilseconazole, Inhibitor
Quilseconazole
Purity
>98% (HPLC)
Synonyms
Quilseconazole; VT-1129; VT1129; inhibitor
Purity/Purification
>98% (HPLC)
Suitability
10mM in DMSO
Target
Fungal
Receptor
Fungal
Chemical Name
(2R)-2-(2, 4-difluorophenyl)-1, 1-difluoro-3-(1H-tetrazol-1-yl)-1-{5-[4-(trifluoromethoxy)phenyl]pyridin-2-yl}propan-2-ol
SMILES
O[C@@](CN1N=NN=C1)(C2=CC=C(F)C=C2F)C(F)(F)C3=NC=C(C4=CC=C(OC(F)(F)F)C=C4)C=C3
Molecular Formula
C22H14F7N5O2
CAS Number
1340593-70-5
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Quilseconazole, inhibitor
A novel selective, orally available fungal CYP51 (lanosterol 14-alpha-demethylase) inhibitor; displays greater selectivity for fungal enzyme than for mammalian CYP450 compared to the approved azole class of antifungal drugs; inhibits C. albicans and T. rubrum with MIC of
Product Categories/Family for Quilseconazole, inhibitor
References
1. Hoekstra WJ, et al. Bioorg Med Chem Lett. 2014 Aug 1; 24 (15):3455-8.
2. Lockhart SR, et al. Antimicrob Agents Chemother. 2016 Mar 25; 60 (4):2528-31.
3. Warrilow AG, et al. Antimicrob Agents Chemother. 2016 Jul 22; 60 (8):4530-8.
4. Nielsen K, et al. Med Mycol. 2017 Jun 1; 55 (4):453-456.
2. Lockhart SR, et al. Antimicrob Agents Chemother. 2016 Mar 25; 60 (4):2528-31.
3. Warrilow AG, et al. Antimicrob Agents Chemother. 2016 Jul 22; 60 (8):4530-8.
4. Nielsen K, et al. Med Mycol. 2017 Jun 1; 55 (4):453-456.
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Product Notes
The Quilseconazole (Catalog #AAA3601366) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Quilseconazole, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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