Testing Data
Okadaic acid, free acid, Inhibitor
Okadaic acid, free acid
Purity
>98% (TLC)
Synonyms
Okadaic acid; free acid; inhibitor
Purity/Purification
>98% (TLC)
Specific Activity
PP2A and PP1 inhibitor
CAS Registry Number
78111-17-8
Molecular Formula
C44H68O13
Solubility
May be dissolved in DMSO (40mg/ml); or Ethanol (5mg/ml)
Preparation and Storage
Store desiccated as supplied at -20 degree C for up to 2 years. Store solutions at -20o for up to 1 month.
Testing Data
Testing Data
Related Product Information for Okadaic acid, free acid, inhibitor
A naturally occurring polyether marine toxin. Potent and selective inhibitor of protein phosphatases inhibiting PP2A completely at 1nM and PP1 at higher concentrations, while PP2C is not inhibited. It is an extremely useful tool for studying cellular protein phosphorylation (2). Induces apoptosis in a variety of cell types (3). Activates atypical protein kinase isotypes and induces insulin-like effects in adipocytes (4).
Product Categories/Family for Okadaic acid, free acid, inhibitor
References
1. P Cohen et al. Trends Biochem. Sci.1990 15:98.
2. DG Hardie et al. Methods Ezymol.1991 201:469.
3. TJ Haneji et al. Int. J. Oncol. 2013 42:1904.
4. ML Standaert et al. J. Biol. Chem. 1999 274:14074.
2. DG Hardie et al. Methods Ezymol.1991 201:469.
3. TJ Haneji et al. Int. J. Oncol. 2013 42:1904.
4. ML Standaert et al. J. Biol. Chem. 1999 274:14074.
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Product Notes
The Okadaic acid, free acid (Catalog #AAA516402) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Okadaic acid, free acid, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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