Formula
NVP-AAM077, inhibitor
NVP-AAM077
Purity
98.0%
Synonyms
NVP-AAM077; inhibitor
Purity/Purification
98.0%
Form/Format
POWDER
CAS
459836-30-7
Molecular Formula
C17H17BrN3O5P
Receptor
hNMDA 1A/2A receptors
270nM
270nM
Bioactivity
PEAQX (NVP-AAM 077) is a potent and orally active NMDA antagonist with a 15-fold preference for human NMDA receptors with the 1A/2A (IC50=270 nM), rather than 1A/2B (29,600 nM).
Solubility
DMSO
10 mM ( > 1 mg/ml refers to the product slightly soluble or insoluble)
10 mM ( > 1 mg/ml refers to the product slightly soluble or insoluble)
HNMR
Consistent with structure
HPLC
Consistent with structure
Preparation and Storage
3 years -20°C powder
Formula
Formula
Related Product Information for NVP-AAM077, inhibitor
PEAQX(NVP-AAM 077) is an effective and orally available NMDA antagonist. It can inhibit human NMDA receptors for 1A/2A(IC50: 270 nM), rather than 1A/2B(29,600 nM).
References
1. Auberson YP, et al. 5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition. Bioorg Med Chem Lett. 2002 Apr 8; 12 (7):1099-102.
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Product Notes
The NVP-AAM077 (Catalog #AAA5750034) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "NVP-AAM077, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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