Myricanone, Inhibitor
Myricanone
Purity
98.00%
Synonyms
Myricanone; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C21H24O5
CAS Number
32492-74-3
Target & IC50
Bcl-2
Caspase
Estrogen receptor
HSP90
NF-kappaB
Progestogen receptor
ROS
STAT
Caspase
Estrogen receptor
HSP90
NF-kappaB
Progestogen receptor
ROS
STAT
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Related Product Information for Myricanone, inhibitor
Myricanone has antioxidant, and anticancer activities, it has apoptosis-promoting ability by triggering caspase activation, and suppression of cell proliferation by down-regulation of NF-kappaB and STAT3 signalling cascades. Myricanone shows in vitro testosterone 5alpha-reductase inhibitory activity and in vivo anti-androgenic activity using growth of flank organ in castrated Syrian hamsters and/or hair regrowth after shaving in testosterone-treated C57Black/6CrSlc mice.
Product Categories/Family for Myricanone, inhibitor
References
In vitro Anticancer Activity of Myricanone in Human Lung Adenocarcinoma A549 Cells. Chemotherapy. 2014;60(2):81-7.
Anticancer potential of myricanone, a major bioactive component of Myrica cerifera: novel signaling cascade for accomplishing apoptosis. J Acupunct Meridian Stud. 2013 Aug;6(4):188-98.
Anti-androgenic activity of Myricae Cortex--isolation of active constituents from bark of Myrica rubra. Biol Pharm Bull. 2001 Mar;24(3):259-63.
Anticancer potential of myricanone, a major bioactive component of Myrica cerifera: novel signaling cascade for accomplishing apoptosis. J Acupunct Meridian Stud. 2013 Aug;6(4):188-98.
Anti-androgenic activity of Myricae Cortex--isolation of active constituents from bark of Myrica rubra. Biol Pharm Bull. 2001 Mar;24(3):259-63.
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Product Notes
The Myricanone (Catalog #AAA5762809) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Myricanone, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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