Mussaenoside, Inhibitor
Mussaenoside
Purity
98.00%
Synonyms
Mussaenoside; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C17H26O10
SMILES
C[C@](CC[C@H]12)([C@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)O[C@H](CO)[C@H]2O)OC=C1C(OC)=O)O
CAS Number
64421-27-8
Target & IC50
TNF-alpha
IL Receptor
NF-kappaB
IL Receptor
NF-kappaB
In Vitro
The ethanolic extract of the aerial parts of Castilleja tenuiflora was separated by silica gel column chromatography. The fractions were evaluated using the induced edema acetate 12-O-tetradecanoylphorbol (TPA) anti-inflammatory activity model. The most active fraction was subjected to medium-pressure liquid chromatography (MPLC) with UV detection at 206 and 240nM. The following iridoids were isolated: geniposidic acid, aucubin, bartioside, 8-epi-loganin, Mussaenoside, and the phenylpropanoid verbascoside. The most active iridoid was geniposidic acid, which was more active than the control (indomethacin), and the least active iridoid was Mussaenoside. 8-epi-Loganin, and Mussaenoside have not been previously reported to be anti-inflammatory compounds[1]
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Related Product Information for Mussaenoside, inhibitor
Mussaenoside has anti-inflammatory action, the mechanism associated with downregulation of nuclear factor-kappaB.
Product Categories/Family for Mussaenoside, inhibitor
References
Anti-inflammatory activity of iridoids and verbascoside isolated from Castilleja tenuiflora.Molecules. 2013 Sep 30;18(10):12109-18.
Anti-inflammatory activity of iridoids and verbascoside isolated from Castilleja tenuiflora.Molecules. 2013 Sep 30;18(10):12109-18.
The Herbal Drug Melampyrum pratense L. (Koch): Isolation and Identification of Its Bioactive Compounds Targeting Mediators of Inflammation.Evid Based Complement Alternat Med. 2013;2013:395316.
Anti-inflammatory activity of iridoids and verbascoside isolated from Castilleja tenuiflora.Molecules. 2013 Sep 30;18(10):12109-18.
The Herbal Drug Melampyrum pratense L. (Koch): Isolation and Identification of Its Bioactive Compounds Targeting Mediators of Inflammation.Evid Based Complement Alternat Med. 2013;2013:395316.
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Product Notes
The Mussaenoside (Catalog #AAA5760678) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Mussaenoside, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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