Structure
Mocetinostat, Inhibitor
Mocetinostat
Purity
>98% (HPLC)
Synonyms
Mocetinostat; MGCD0103;mgCD 0103;mgCD-0103; inhibitor
Purity/Purification
>98% (HPLC)
Suitability
10mM in DMSO
Target
HDAC
Receptor
HDAC1; HDAC11; HDAC2; HDAC3; HDAC4
Chemical Name
Benzamide, N-(2-aminophenyl)-4-[[[4-(3-pyridinyl)-2-pyrimidinyl]amino]methyl]
SMILES
NC1=CC=CC=C1NC(=O)C1=CC=C(CNC2=NC=CC(=N2)C2=CN=CC=C2)C=C1
Molecular Formula
C23H20N6O
CAS Number
726169-73-9
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Mocetinostat, inhibitor
An isotype-selective small molecule HDAC inhibitor that selectively inhibits HDAC1 (IC50=0.15uM); also inhibits HDAC2/3/11; no effect on HDAC4/5/6/7/8; induces hyperacetylation of histones and caused cell cycle blockade in various human cancer cell lines; inhibits growth of human tumor xenografts in nude mice; orally bioactive. Blood Cancer Phase 2 Clinical
Product Categories/Family for Mocetinostat, inhibitor
References
1. Fournel M, et al. Mol Cancer Ther. 2008 Apr; 7 (4):759-68.
2. Zhou N, et al. J Med Chem. 2008 Jul 24; 51 (14):4072-5.
3. Raeppel S, et al. Bioorg Med Chem Lett. 2009 Feb 1; 19 (3):644-9.
2. Zhou N, et al. J Med Chem. 2008 Jul 24; 51 (14):4072-5.
3. Raeppel S, et al. Bioorg Med Chem Lett. 2009 Feb 1; 19 (3):644-9.
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Product Notes
The Mocetinostat (Catalog #AAA3605779) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Mocetinostat, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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