Chemical Structure
LY294002, Inhibitor
LY294002
Purity
>98%
Synonyms
LY294002; inhibitor
Purity/Purification
>98%
Form/Format
Powder
Concentration
0.1 mM: 32.54 mL (1 mg); 162.71 mL (5 mg); 325.41mL (10 mg)
0.5 mM: 6.51 mL (1 mg); 32.54 mL (5 mg); 65.08 mL (10 mg)
1 mM: 3.25 mL (1 mg); 16.27 mL (5 mg); 32.54 mL (10 mg)
5 mM: 0.65 mL (1 mg); 3.25 mL (5 mg); 6.51 mL (10 mg) (varies by lot)
0.5 mM: 6.51 mL (1 mg); 32.54 mL (5 mg); 65.08 mL (10 mg)
1 mM: 3.25 mL (1 mg); 16.27 mL (5 mg); 32.54 mL (10 mg)
5 mM: 0.65 mL (1 mg); 3.25 mL (5 mg); 6.51 mL (10 mg) (varies by lot)
CAS Number
154447-36-6
Formula
C19H17NO3
SMILES
C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC=C4
Actions
Inhibitor
In Vivo Solvent
1% DMSO/30% polyethylene glycol/1% Tween 80
Solubility (DMSO)
36 mg/mL (117.13 mM)
Solubility (Ethanol)
21 mg/mL (68.32 mM)
Solubility (in vivo)
30 mg/mL
Solubility (Water)
<1 mg/mL (<1 mM)
Availability
We cannot ship this item to Switzerland, Italy, Germany, France and Austria.
Preparation and Storage
at -20 degree C 3 years Powder
Chemical Structure
Chemical Structure
Related Product Information for LY294002, inhibitor
LY294002 is a PI3k inhibitor (cell IC50 about 10 μM) and a casein kinase II inhibitor.
References
Daniel Limonta, .et al. Fibroblast growth factor 2 enhances Zika virus infection in human fetal brain, J Infect Dis, 2019, 2019 PMID: 30799482
Lv H, .et al. CXCL8 gene silencing promotes neuroglial cells activation while inhibiting neuroinflammation through the PI3K/Akt/NF-κB-signaling pathway in mice with ischemic stroke, J Cell Physiol, 2018, Oct 26 PMID: 30362547
Hui Liang, .et al. Targeting the PI3K/AKT pathway via GLI1 inhibition enhanced the drug sensitivity of acute myeloid leukemia cells, Sci Rep, 2017, 7: 40361 PMID: 28098170
Lv H, .et al. CXCL8 gene silencing promotes neuroglial cells activation while inhibiting neuroinflammation through the PI3K/Akt/NF-κB-signaling pathway in mice with ischemic stroke, J Cell Physiol, 2018, Oct 26 PMID: 30362547
Hui Liang, .et al. Targeting the PI3K/AKT pathway via GLI1 inhibition enhanced the drug sensitivity of acute myeloid leukemia cells, Sci Rep, 2017, 7: 40361 PMID: 28098170
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Product Notes
The LY294002 (Catalog #AAA385534) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "LY294002, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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