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Chemical Structure

Indophagolin, Inhibitor

Indophagolin

Purity
0.9784
Synonyms
Indophagolin; inhibitor
Ordering
For Research Use Only!
Purity/Purification
0.9784
Form/Format
Solid
Solubility
DMSO: 10mM
(<1mg/ml refers to the product slightly soluble or insoluble)
SMILES
O=S(C1=CC2=C(C=C1Br)CCN2C(C3CC3)=O)(NC4=CC=C(Cl)C(C(F)(F)F)=C4)=O
Formula
C19H15BrClF3N2O3S
CAS Number
1207660-00-1
Preparation and Storage
Store at 0-4 degree C for short term (days to weeks), or -20 degree C for long term (months).

Chemical Structure

Chemical Structure
Related Product Information for Indophagolin, inhibitor
Indophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 . Indophagolin antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71,2.40 and 3.49uM, respectively.
Product Categories/Family for Indophagolin, inhibitor
References
Carnero Corrales MA, et al. Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin [published online ahead of print, 2021 Mar 9]. Cell Chem Biol. 2021;S2451-9456(21)00102-1.

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Product Notes

The Indophagolin (Catalog #AAA5765085) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Indophagolin, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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