Testing Data
GSK1904529A, inhibitor
GSK1904529A
Purity
>99%
Synonyms
GSK1904529A; inhibitor
Purity/Purification
>99%
Formula
C44H47F2N9O5S
CAS Number
1089283-49-7
Preparation and Storage
Store at-20 degree C 2 years.
Testing Data
Testing Data
Related Product Information for GSK1904529A, inhibitor
GSK1904529A, which potently inhibits IGF-IR (IC50= 27 nmol/L) and IR (IC50= 25 nmol/L) activities in vitro and in vivo, is a promising candidate for therapeutic use in solid and hematologic cancers. [1] IC50s for GSK1904529A in tumor cell lines ranged from 35 nmol/L to >30 umol/L.The tumor histologic types showing the greatest sensitivity to this compound were Ewing's sarcoma and multiple myeloma, where IC50s in three of five Ewing's sarcoma cell lines were <100 nmol/L and IC50s in five of eight multiple myeloma cell lines were <200 nmol/L.[1] Oral administration of GSK1904529A decreases the growth of human tumor xenografts in mice.[1]
Product Categories/Family for GSK1904529A, inhibitor
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Product Notes
The GSK1904529A (Catalog #AAA8506357) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "GSK1904529A, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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