Structure
Fadrozole hydrochloride, Inhibitor
Fadrozole hydrochloride
Purity
98.00%
Synonyms
Fadrozole hydrochloride; CGS 16949A; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
DMSO: 100mg/mL (385.02mM)
H2O: 100mg/mL (385.02mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
H2O: 100mg/mL (385.02mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C14H14ClN3
SMILES
Cl.N#Cc1ccc(C2CCCc3cncn32)cc1
CAS Number
102676-31-3
Target & IC50
aromatase: ic50 1.4nM (rat)
In Vitro
Fadrozole hydrochloride inhibits growth of androstenedione-stimulated mammary D2 cells implanted into thoracic mammary fat pads of mice by 95% when administered at a dose of 0.5 mg per animal per day.
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Structure
Structure
Related Product Information for Fadrozole hydrochloride, inhibitor
Fadrozole hydrochloride is a model aromatase inhibitor that has been shown to suppress estrogen production in the ovaries of fish.
Product Categories/Family for Fadrozole hydrochloride, inhibitor
References
Tekmal R R, Durgam V R. A novel in vitro and in vivo breast cancer model for testing inhibitors of estrogen biosynthesis and its action using mammary tumor cells with an activated int-5/aromatase gene[J]. Cancer Letters, 1997, 118(1):0-28.
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Product Notes
The Fadrozole hydrochloride (Catalog #AAA5758444) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Fadrozole hydrochloride, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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