Eriodictyol-7-O-glucoside, Inhibitor

Eriodictyol-7-O-glucoside

Purity

98.00%

Synonyms

Eriodictyol-7-O-glucoside; inhibitor

Ordering
Cat. Num. AAA5760352 For Research Use Only!

Purity/Purification

98.00%

Form/Format

Solid. Powder

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C21H22O11

SMILES

OC[C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1Oc1cc(O[C@@H](CC2=O)c(cc3)cc(O)c3O)c2c(O)c1

CAS Number

38965-51-4

Target & IC50

Nrf2

In Vitro

Eriodictyol-7-O-glucoside as a novel nuclear factor E2-related factor 2 (Nrf2) activator using a high-throughput cellular screening method. This compound activated Nrf2 signaling pathway and was able to stabilize Nrf2 by delaying Nrf2 degradation, resulting in accumulation of Nrf2 protein and activation of the Nrf2-dependent protective response. Recent studies have suggested that activation of Nrf2 pathway would confer protection against cisplatin-induced toxicity. The protective role of Eriodictyol-7-O-glucoside in cisplatin-induced toxicity was investigated in a human renal mesangial cell line, HRMC. Co-treatment of HRMC cells with Eriodictyol-7-O-glucoside significantly improved cell survival under cisplatin exposure[1]

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Related Product Information for Eriodictyol-7-O-glucoside, inhibitor

Eriodictyol-7-O-glucoside and epicatechin appears to be responsible for the antioxidant activity of pistachio skin.

Product Categories/Family for Eriodictyol-7-O-glucoside, inhibitor

Immunology/Inflammation; Nrf2

References

Eriodictyol-7-O-glucoside, a novel Nrf2 activator, confers protection against cisplatin-induced toxicity.Food Chem Toxicol. 2012 Jun;50(6):1927-32.
Eriodictyol-7-O-glucoside, a novel Nrf2 activator, confers protection against cisplatin-induced toxicity.Food Chem Toxicol. 2012 Jun;50(6):1927-32.
Antioxidant activity and phenolic profile of pistachio (Pistacia vera L., variety Bronte) seeds and skins. Biochimie. 2010 Sep;92(9):1115-22.

Similar Products

Calycosin-7-O-beta-D-glucoside Biochemical

Host: n/a

Reactivity: n/a

Apps: n/a

Product Notes

The Eriodictyol-7-O-glucoside (Catalog #AAA5760352) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Eriodictyol-7-O-glucoside, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Eriodictyol-7-O-glucoside, Inhibitor